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使用 Clarus 眼底相机进行广角成像与裂隙灯眼底检查在评估国家卫生服务糖尿病视网膜病变筛查计划转介患者中的比较。

Widefield imaging with Clarus fundus camera vs slit lamp fundus examination in assessing patients referred from the National Health Service diabetic retinopathy screening programme.

机构信息

Moorfields Eye Hospital NHS Foundation Trust, London, UK.

出版信息

Eye (Lond). 2021 Jan;35(1):299-306. doi: 10.1038/s41433-020-01218-x. Epub 2020 Oct 20.

DOI:10.1038/s41433-020-01218-x
PMID:33082533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7574390/
Abstract

OBJECTIVES

To compare diabetic retinopathy (DR) grading and management plan between virtual review using widefield Clarus imaging and macular optical coherence tomography (OCT) versus slit lamp clinical examination and macular OCT.

METHOD

New referrals over 3 months from the National Diabetic Eye Screening programme (DESP) were screened. Patients who had both Clarus widefield imaging and macular OCT were included. All patients underwent slit lamp examination in clinic. Data obtained from electronic patient records included referral reason, DR grading and management plan. Two graders retrospectively reviewed imaging and formulated a management plan blinded to results from patients' clinic visit. Results from virtual examination were compared with those from slit lamp examination.

RESULTS

One-hundred and two eyes of 51 patients were assessed. 11 fundus photos from 7 patients and 15 fundus photos from 10 patients were deemed inadequate by grader G1 and G2, respectively. Eighteen (35%) patients and 11 (22%) patients from virtual assessment by G1 and G2, respectively were found to need a face a face appointment to aid diagnosis. Compared to slit lamp examination, 15% and 7.5% of patients from G1 and G2's virtual assessment respectively had different proposed management plan. Agreement of DR grading between both virtual graders and slit lamp examination was fair (Kappa's coefficient = 0.56). One case of slit lamp noted retinal neovascularization, which was graded as background retinopathy by DESP was also graded as such on virtual assessment.

CONCLUSION

Widefield Clarus and OCT imaging allowed two-thirds of DESP referrals to be safely managed virtually.

摘要

目的

比较使用宽视野 Clarus 成像和黄斑光学相干断层扫描 (OCT) 进行虚拟检查与裂隙灯临床检查和黄斑 OCT 检查在糖尿病视网膜病变 (DR) 分级和管理计划方面的差异。

方法

对国家糖尿病眼病筛查计划 (DESP) 3 个月内的新转诊患者进行筛查。纳入同时进行 Clarus 宽视野成像和黄斑 OCT 检查的患者。所有患者均在诊所接受裂隙灯检查。从电子病历中获取的数据包括转诊原因、DR 分级和管理计划。两名分级员回顾性地查看图像并制定管理计划,对患者就诊结果进行盲法评估。将虚拟检查的结果与裂隙灯检查的结果进行比较。

结果

评估了 51 名患者的 102 只眼。7 名患者的 11 张眼底照片和 10 名患者的 15 张眼底照片分别被分级员 G1 和 G2 认为不充分。18 名(35%)患者和 11 名(22%)患者分别需要面对面就诊以协助诊断,这是 G1 和 G2 通过虚拟评估发现的。与裂隙灯检查相比,G1 和 G2 虚拟评估的 15%和 7.5%的患者分别有不同的建议管理计划。两位虚拟分级员与裂隙灯检查的 DR 分级一致性为中等(Kappa 系数=0.56)。一例裂隙灯检查发现的视网膜新生血管,DESP 被评为背景性视网膜病变,在虚拟评估中也被评为背景性视网膜病变。

结论

宽视野 Clarus 和 OCT 成像使三分之二的 DESP 转诊患者可以安全地进行虚拟管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5306/7574390/d6419007b4ef/41433_2020_1218_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5306/7574390/d6419007b4ef/41433_2020_1218_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5306/7574390/d6419007b4ef/41433_2020_1218_Fig1_HTML.jpg

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