Fallatah Anas M, Bifari Anas E, Alshehri Hisham Z, Wali Sahal M, Alghamdi Saleh A, Almusallam Sultan A, Al-Abbadi Wid S, Albasri Samera
College of Medicine, King Abdulaziz University, Jeddah, SAU.
Department of Radiology, King Abdulaziz University Hospital, Jeddah, SAU.
Cureus. 2020 Sep 16;12(9):e10493. doi: 10.7759/cureus.10493.
Background Iron deficiency is the most common etiology of anemia among pregnant women. Many studies showed that anemia during pregnancy had been associated with adverse outcomes such as intrauterine growth retardation, preterm delivery, and maternal mortality. However, screening for those pregnant remains controversial. Objectives To find the prevalence of anemia among pregnant women and pregnancy outcomes. Also, to find the cost-effectiveness of running complete blood count (CBC) tests among them. Methods This is a retrospective record review done on pregnant women who delivered at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, between January 1, 2018, and December 31, 2018. They were screened for eligibility, with the exclusion of those with hemoglobinopathies such as sickle cell anemia and thalassemia. Data were collected from their electronic medical records. Results A total of 5,120 pregnant women had delivered from January 1, 2017, to August 31, 2018, and 2,845 (55.6%) developed anemia during pregnancy. Out of 2,822, 2,301 were mild, 471 moderate, 50 severe, and 2,185 were normal. A total of 3,656 (71.4%) women were Saudis, and 1,464 (28.6%) were non-Saudis. The mean age was 29.85±6 years, and their first hemoglobin reading mean was 10.6±1.3g/dl. Out of 2,822, 546 developed undesired pregnancy outcomes. History of anemia, blood transfusion, intrauterine fetal demise, and stillbirth was significantly associated with abnormal hemoglobin levels (p<0.05). Complete blood count (CBC) testing for these pregnant women cost 422,990.92 US dollars. Conclusion Although the cut-off point of diagnosing anemia level during pregnancy isn't fully understood, pregnant women with mild to moderate levels appeared to have lesser adverse pregnancy outcomes in comparison to women with severe level. Therefore, screening during prenatal visits or antenatal for anemia should be tailored to each pregnant based on her condition and the overall clinical judgment.
背景 缺铁是孕妇贫血最常见的病因。许多研究表明，孕期贫血与不良结局相关，如胎儿宫内生长受限、早产和孕产妇死亡。然而，对这些孕妇进行筛查仍存在争议。 目的 了解孕妇贫血的患病率及妊娠结局。此外，了解对她们进行全血细胞计数（CBC）检测的成本效益。 方法 这是一项对2018年1月1日至2018年12月31日在沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院分娩的孕妇进行的回顾性记录审查。对她们进行资格筛查，排除患有血红蛋白病如镰状细胞贫血和地中海贫血的孕妇。数据从她们的电子病历中收集。 结果 2017年1月1日至2018年8月31日共有5120名孕妇分娩，其中2845名（55.6%）在孕期发生贫血。在2822名贫血孕妇中，2301名轻度贫血，471名中度贫血，50名重度贫血，2185名正常。共有3656名（71.4%）女性为沙特人，1464名（28.6%）为非沙特人。平均年龄为29.85±6岁，她们首次血红蛋白读数的平均值为10.6±1.3g/dl。在2822名孕妇中，546名出现了不良妊娠结局。贫血史、输血史、胎儿宫内死亡和死产与血红蛋白水平异常显著相关（p<0.05）。对这些孕妇进行全血细胞计数检测花费422,990.92美元。 结论 尽管孕期贫血诊断水平的临界点尚未完全明确，但与重度贫血孕妇相比，轻度至中度贫血孕妇的不良妊娠结局似乎较少。因此，产前检查或孕期贫血筛查应根据每位孕妇的情况和整体临床判断进行量身定制。
