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一例腺病毒感染后支气管扩张症患者在家中使用高流量湿化鼻导管(HHFNC)进行治疗。

A case of post adenoviral bronchiectasis being managed at home with humidified high flow nasal cannula (HHFNC).

作者信息

Singh Divya, Rajbanshi Argha, Giri Prabhas Prasun

机构信息

Junior Resident, Institute of Child Health, India.

Associate Professor and Incharge of Pediatric Intensive Care Unit, Institute of Child Health, India.

出版信息

Respir Med Case Rep. 2020 Sep 28;31:101233. doi: 10.1016/j.rmcr.2020.101233. eCollection 2020.

DOI:10.1016/j.rmcr.2020.101233
PMID:33083219
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7552089/
Abstract

Human adenovirus is an important cause of febrile illness affecting mainly respiratory system ranging from pharyngitis, coryza to fatal pneumonia. Though most of the infections are trivial and results in complete recovery but it may result in considerable morbidities and mortalities in selected patients who developed severe adenoviral infections especially Pneumonia(ADVP)/Lower respiratory tract infection(LRTI). Severe adenoviral pneumonia is notorious to produce long term sequelae in the form of post infectious bronchiolitis obliterans (PIBO) or even bronchiectasis. Here we present a case of a ten months old boy developed bronchiectasis as a sequela of severe adenoviral LRTI and needed prolonged and recurrent respiratory support in the pediatric intensive care unit(PICU) and ultimately discharged on home Humidified high flow nasal cannula(HHFNC).

摘要

人腺病毒是引起发热性疾病的重要病因,主要影响呼吸系统,范围从咽炎、鼻炎到致命性肺炎。尽管大多数感染症状轻微且可完全康复,但在某些发生严重腺病毒感染尤其是肺炎(腺病毒肺炎)/下呼吸道感染(LRTI)的患者中,可能导致相当高的发病率和死亡率。严重的腺病毒肺炎以感染后闭塞性细支气管炎(PIBO)甚至支气管扩张的形式产生长期后遗症而臭名昭著。在此,我们报告一例10个月大男孩,因严重腺病毒LRTI后遗症而发生支气管扩张,在儿科重症监护病房(PICU)需要长期反复的呼吸支持,最终在家中使用高流量加温湿化鼻导管(HHFNC)出院。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f0/7552089/13bdf9391c32/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f0/7552089/82d15a006482/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f0/7552089/1e969d9de530/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f0/7552089/13bdf9391c32/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f0/7552089/82d15a006482/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f0/7552089/1e969d9de530/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f0/7552089/13bdf9391c32/gr3.jpg

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Crit Care Explor. 2019 Aug 1;1(8):e0026. doi: 10.1097/CCE.0000000000000026. eCollection 2019 Aug.
2
A nationwide survey on the use of heated humidified high flow oxygen therapy on the paediatric wards in the UK: current practice and research priorities.一项关于英国儿科病房使用热湿高流量氧疗的全国性调查:当前的实践和研究重点。
BMC Pediatr. 2020 Mar 6;20(1):109. doi: 10.1186/s12887-020-1998-1.
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Epidemiology, clinical presentation and respiratory sequelae of adenovirus pneumonia in children in Kuala Lumpur, Malaysia.
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PLoS One. 2018 Oct 15;13(10):e0205795. doi: 10.1371/journal.pone.0205795. eCollection 2018.
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High flow nasal cannula in children: a literature review.儿童高流量鼻导管吸氧:文献综述
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Prevalence of adenovirus in children with acute respiratory tract infection in Lanzhou, China.中国兰州急性呼吸道感染儿童中腺病毒的流行情况。
Virol J. 2013 Aug 29;10:271. doi: 10.1186/1743-422X-10-271.
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Adenovirus infection with serious pulmonary sequelae in Korean children.韩国儿童腺病毒感染伴严重肺部后遗症
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