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乙酰胆碱作为脊椎动物视网膜中的一种神经递质。

Acetylcholine as a neurotransmitter in the vertebrate retina.

作者信息

Hutchins J B

机构信息

Department of Cell Biology, Vanderbilt University School of Medicine, Nashville, TN 37232.

出版信息

Exp Eye Res. 1987 Jul;45(1):1-38. doi: 10.1016/s0014-4835(87)80075-1.

DOI:10.1016/s0014-4835(87)80075-1
PMID:3308499
Abstract

The evidence for the existence of acetylcholine as a neurotransmitter in the vertebrate retina is reviewed. There is evidence for the existence of a cholinergic system in every retina studied to date; therefore, it appears that acetylcholine is both essential and ubiquitous at this level of the visual system. Particular attention is directed to descriptions of the possible functions of acetylcholine in the retina, and formation of testable models which will serve to elucidate some of the details of cholinergic neurotransmission in the retina.

摘要

本文综述了乙酰胆碱作为脊椎动物视网膜神经递质存在的证据。迄今为止,在所有已研究的视网膜中都有证据表明存在胆碱能系统;因此,在视觉系统的这一水平上,乙酰胆碱似乎既是必不可少的,也是普遍存在的。本文特别关注乙酰胆碱在视网膜中可能功能的描述,以及可测试模型的形成,这些模型将有助于阐明视网膜中胆碱能神经传递的一些细节。

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Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.Munc13 异构体在视网膜突触中的异质前突触分布及具有 Munc13 异构体双重表达的非传统双极细胞类型的鉴定:使用 Munc13-EXFP 敲入小鼠的研究。
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