第 26 届前列腺癌基金会科学研讨会报告。

Science Department, Prostate Cancer Foundation, Santa Monica, California, USA.

Prostate. 2021 Jan;81(1):3-19. doi: 10.1002/pros.24083. Epub 2020 Oct 21.

BACKGROUND

The 26th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held from October 24-26, 2019 in Carlsbad, CA.

METHODS

The Annual PCF Scientific Retreat is a global scientific research conference that focuses on the most promising and interesting new research in the prostate cancer field, and topics arising from other fields that have the potential to impact and advance prostate cancer research and clinical care.

RESULTS

The primary topic areas addressed at the 2019 PCF Retreat included: (i) new insights into prostate cancer biology and treatment; (ii) new drugs and drug targets in prostate cancer; (iii) advances in prostate cancer genomics; (iv) lessons from the multi-arm, multistage randomized phase 3 STAMPEDE trial; (v) advances in immunotherapy for prostate cancer; (vi) factors contributing to prostate cancer racial disparities; (vii) treatment-associated small-cell/neuroendocrine prostate cancer (t-SCNC); (viii) artificial intelligence and machine learning in cancer research and development; (ix) population science research on prostate cancer; and (x) prostate cancer research in the Department of Veterans Affairs.

CONCLUSIONS

This article reviews the presentations from the 2019 PCF Scientific Retreat. We hope that this knowledge will accelerate research leading to new understandings of prostate cancer biology and improve treatments for patients with prostate cancer.

背景

第 26 届前列腺癌基金会（PCF）科学研讨会于 2019 年 10 月 24 日至 26 日在加利福尼亚州卡尔斯巴德举行。

方法

年度 PCF 科学研讨会是一个全球性的科学研究会议，专注于前列腺癌领域最有前途和最有趣的新研究，以及来自其他领域的有可能影响和推动前列腺癌研究和临床护理的主题。

结果

2019 年 PCF Retreat 重点讨论的主要主题领域包括：（i）前列腺癌生物学和治疗的新见解；（ii）前列腺癌的新药和药物靶点；（iii）前列腺癌基因组学的进展；（iv）来自多臂、多阶段随机 3 期 STAMPEDE 试验的经验教训；（v）前列腺癌免疫治疗的进展；（vi）导致前列腺癌种族差异的因素；（vii）与治疗相关的小细胞/神经内分泌前列腺癌（t-SCNC）；（viii）癌症研究和开发中的人工智能和机器学习；（ix）前列腺癌的人群科学研究；以及（x）退伍军人事务部的前列腺癌研究。