Department of Science, Prostate Cancer Foundation, Santa Monica, California, USA.
Prostate. 2024 Oct;84(14):1271-1289. doi: 10.1002/pros.24768. Epub 2024 Jul 17.
The 30th Annual Prostate Cancer Foundation (PCF) Scientific Retreat was held at the Omni La Costa Resort in Carlsbad, CA, from October 26 to 28, 2023. A hybrid component was included for virtual attendees.
The Annual PCF Scientific Retreat is a leading international scientific conference focused on pioneering, unpublished, and impactful studies across the spectrum of basic through clinical prostate cancer research, as well as research from related fields with significant potential for improving prostate cancer research and patient outcomes.
The 2023 PCF Retreat concentrated on key areas of research, including: (i) the biology of cancer stem cells and prostate cancer lineage plasticity; (ii) mechanisms of treatment resistance; (iii) emerging AI applications in diagnostic medicine; (iv) analytical and computational biology approaches in cancer research; (v) the role of nerves in prostate cancer; (vi) the biology of prostate cancer bone metastases; (vii) the contribution of ancestry and genomics to prostate cancer disparities; (viii) prostate cancer 3D genomics; (ix) progress in new targets and treatments for prostate cancer; (x) the biology and translational applications of tumor extracellular vesicles; (xi) updates from PCF TACTICAL Award teams; (xii) novel platforms for small molecule molecular glues and binding inhibitors; and (xiii) diversity, equity and inclusion strategies for advancing cancer care equity.
This meeting report summarizes the presentations and discussions from the 2023 PCF Scientific Retreat. We hope that sharing this information will deepen our understanding of current and emerging research and drive future advancements in prostate cancer patient care.
第 30 届前列腺癌基金会（PCF）科学研讨会于 2023 年 10 月 26 日至 28 日在加利福尼亚州卡尔斯巴德的 Omni La Costa 度假村举行。会议还包括虚拟与会者的混合组件。
年度 PCF 科学研讨会是一个领先的国际科学会议，专注于开创性、未发表和有影响力的研究，涵盖从基础到临床前列腺癌研究的各个方面，以及来自具有显著改善前列腺癌研究和患者结果潜力的相关领域的研究。
2023 年 PCF Retreat 集中在以下关键研究领域：（i）癌症干细胞和前列腺癌谱系可塑性的生物学；（ii）治疗抵抗的机制；（iii）诊断医学中新兴 AI 应用；（iv）癌症研究中的分析和计算生物学方法；（v）神经在前列腺癌中的作用；（vi）前列腺癌骨转移的生物学；（vii）祖先和基因组学对前列腺癌差异的贡献；（viii）前列腺癌 3D 基因组学；（ix）前列腺癌新靶点和治疗方法的进展；（x）肿瘤细胞外囊泡的生物学和转化应用；（xi）来自 PCF TACTICAL 奖团队的更新；（xii）小分子分子胶和结合抑制剂的新平台；以及（xiii）推进癌症护理公平的多样性、公平性和包容性策略。
本会议报告总结了 2023 年 PCF 科学研讨会的演讲和讨论。我们希望分享这些信息将加深我们对当前和新兴研究的理解，并推动前列腺癌患者护理的未来进展。
