Department of Orthopaedic Surgery, Yamagata University Faculty of Medicine, Yamagata-City, Japan.
Department of Orthopaedic Surgery, Yamagata Saisei Hospital, Yamagata-City, Japan.
Mod Rheumatol Case Rep. 2020 Jan;4(1):116-121. doi: 10.1080/24725625.2019.1680135. Epub 2019 Oct 28.
Gouty tophi occur less frequently and disappear only with modern medication therapy for symptomatic or asymptomatic hyperuricaemia. However, the medication may require a long time to take effect due to the systemic urate pool associated with massive gouty tophi. We present the case of a 37-year-old woman who suffered from massive gouty tophi of both feet due to hyperuricaemia. After resection of the massive gouty tophi from her right foot and treatment with uricemia medication, the gouty tophi of her opposite foot disappeared rapidly due to reducing the patient's systemic urate pool with intensification of drug medication.
痛风石在现代药物治疗有症状或无症状高尿酸血症时较少发生，并且仅在这种情况下才会消失。然而，由于与大量痛风石相关的系统性尿酸池，药物可能需要很长时间才能发挥作用。我们报告了一例 37 岁女性因高尿酸血症而患有双脚巨大痛风石的病例。在切除右脚巨大痛风石并接受降尿酸药物治疗后，由于药物治疗的强化降低了患者的系统性尿酸池，她对侧足部的痛风石迅速消失。
