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扩大马拉维农村地区非传染性疾病护理的可及性:综合非传染性疾病-艾滋病模式下的回顾性队列研究结果。

Expanding access to non-communicable disease care in rural Malawi: outcomes from a retrospective cohort in an integrated NCD-HIV model.

机构信息

Partners In Health, Neno, Malawi

Division of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, USA.

出版信息

BMJ Open. 2020 Oct 21;10(10):e036836. doi: 10.1136/bmjopen-2020-036836.

Abstract

OBJECTIVES

Non-communicable diseases (NCDs) account for one-third of disability-adjusted life years in Malawi, and access to care is exceptionally limited. Integrated services with HIV are widely recommended, but few examples exist globally. We report descriptive outcomes from an Integrated Chronic Care Clinic (IC3).

DESIGN

This is a retrospective cohort study.

SETTING

The study includes an HIV-NCD clinic across 14 primary care facilities in the rural district of Neno, Malawi.

PARTICIPANTS

All new patients, including 6233 HIV-NCD diagnoses, enrolled between January 2015 and December 2017 were included. This included 3334 patients with HIV (59.7% women) and 2990 patients with NCD (67.3% women), 10% overall under age 15 years.

INTERVENTIONS

Patients were seen at their nearest health centre, with a hospital team visiting routinely to reinforce staffing. Data were collected on paper forms and entered into an electronic medical record.

PRIMARY AND SECONDARY OUTCOME MEASURES

Routine clinical measurements are reported at 1-year post-enrolment for patients with more than one visit. One-year retention is reported by diagnosis.

RESULTS

NCD diagnoses were 1693 hypertension, 668 asthma, 486 epilepsy, 149 diabetes and 109 severe mental illness. By December 2018, 8.3% of patients with NCD over 15 years were also on HIV treatment. One-year retention was 85% for HIV and 72% for NCDs, with default in 8.4% and 25.5% and deaths in 4.0% and 1.4%, respectively. Clinical outcomes showed statistically significant improvement for hypertension, diabetes, asthma and epilepsy. Of the 1807 (80%) of patients with HIV with viral load results, 85% had undetectable viral load.

CONCLUSIONS

The IC3 model, built on an HIV platform, facilitated rapid decentralisation and access to NCD services in rural Malawi. Clinical outcomes and retention in care are favourable, suggesting that integration of chronic disease care at the primary care level poses a way forward for the large dual burden of HIV and chronic NCDs.

摘要

目的

在马拉维,非传染性疾病(NCDs)占残疾调整生命年的三分之一,而获得医疗的机会极其有限。广泛推荐将艾滋病毒服务综合化,但全球仅有少数范例。我们报告综合慢性护理诊所(IC3)的描述性结果。

设计

这是一项回顾性队列研究。

设置

该研究包括在马拉维农村区 Neno 的 14 个基层医疗设施中的一个艾滋病毒-NCD 诊所。

参与者

所有新患者,包括 2015 年 1 月至 2017 年 12 月期间登记的 6233 例艾滋病毒-NCD 诊断,均包括在内。这包括 3334 名艾滋病毒患者(59.7%为女性)和 2990 名非传染性疾病患者(67.3%为女性),10%的患者总体年龄在 15 岁以下。

干预措施

患者在最近的卫生中心就诊,医院团队定期进行常规访问以加强人员配备。数据记录在纸质表格上,并输入电子病历。

主要和次要结果测量

对多次就诊的患者,在登记后 1 年进行常规临床测量。按诊断报告 1 年保留率。

结果

非传染性疾病诊断为 1693 例高血压、668 例哮喘、486 例癫痫、149 例糖尿病和 109 例严重精神疾病。截至 2018 年 12 月,超过 15 岁的非传染性疾病患者中有 8.3%也在接受艾滋病毒治疗。艾滋病毒的 1 年保留率为 85%,非传染性疾病的保留率为 72%,失访率分别为 8.4%和 25.5%,死亡率分别为 4.0%和 1.4%。高血压、糖尿病、哮喘和癫痫的临床结果显示出统计学上的显著改善。在有病毒载量结果的 1807 名(80%)艾滋病毒患者中,85%的病毒载量无法检测到。

结论

IC3 模型建立在艾滋病毒平台之上,促进了在马拉维农村地区快速分散和获得非传染性疾病服务。临床结果和护理保留率都很有利,这表明在初级保健层面整合慢性病护理是应对艾滋病毒和慢性非传染性疾病双重负担的一种途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2f4/7580053/7ec1ecd2dd5d/bmjopen-2020-036836f01.jpg

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