Agarwal Smital R, Bendgude Vikas D, Kakodkar Pradnya
Department of Pediatric and Preventive Dentistry, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India.
Department of Public Health Dentistry, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India.
J Conserv Dent. 2019 Nov-Dec;22(6):510-515. doi: 10.4103/JCD.JCD_76_20. Epub 2020 Aug 20.
Vitapex has been a popular obturating material for several decades. In recent times, lesion sterilization and tissue repair (LSTR) has shown promising results. This technique uses a mixture of 3 antibiotics for sterilization of the root canals and healing of periradicular tissues.
The objective of this systematic review was to compile all the literature comparing Vitapex and LSTR for pulpally involved primary teeth and evaluate the success rate in terms of clinical and radiographic outcomes.
This review is based on PRISMA guidelines. The electronic search on MEDLINE via PubMed database and Google scholar, cross-referencing and hand search of journals was carried out for articles from January 1, 2000 to December 31, 2019. Articles only in the English language were selected. Out of the 17 articles, 3 unique articles were identified for the review, of which 2 were randomized controlled trials and 1 was a retrospective study.
All the three articles were assessed for their quality and all had a low risk of bias. It was found that LSTR and Vitapex had a high clinical success after 12 months. The radiographic success after 6 months was high but decreased after 12 months in both the groups.
There is no difference in the success rate of LSTR as compared to Vitapex for the treatment of pulpally involved primary teeth.
几十年来，Vitapex一直是一种常用的根管充填材料。近年来，病灶消毒与组织修复（LSTR）已显示出有前景的结果。该技术使用三种抗生素的混合物对根管进行消毒并促进根尖周组织愈合。
本系统评价的目的是汇总所有比较Vitapex和LSTR治疗牙髓受累乳磨牙的文献，并根据临床和影像学结果评估成功率。
本评价基于PRISMA指南。通过PubMed数据库和谷歌学术对MEDLINE进行电子检索，并对2000年1月1日至2019年12月31日的文章进行交叉引用和手工检索期刊。仅选择英文文章。在17篇文章中，确定了3篇独特的文章用于本评价，其中2篇为随机对照试验，1篇为回顾性研究。
对所有三篇文章进行了质量评估，所有文章的偏倚风险均较低。结果发现，LSTR和Vitapex在12个月后均有较高的临床成功率。两组在6个月后的影像学成功率较高，但在12个月后均有所下降。
在治疗牙髓受累乳磨牙方面，LSTR与Vitapex的成功率没有差异。
