Department of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Int J Paediatr Dent. 2012 May;22(3):217-27. doi: 10.1111/j.1365-263X.2011.01181.x. Epub 2011 Sep 23.
To evaluate the clinical and radiographic success rates of three mixed antibiotics in the non-instrumentation endodontic treatment of primary mandibular molars at 24-27 months postoperatively.
Eighty cariously involved lower primary molars from 58 children (ages 3-8 years) received a 3Mix medicament by non-instrumentation endodontic treatment and were then sealed with glass-ionomer cement and composite resin before permanent restoration with stainless steel crowns. The patients received a clinical and radiographic assessment every 6 months over a 2-year follow-up period with an intra-examiner reliability of 0.83-1.00 (κ value).
In 60 cases at 24- to 27-month follow-up, the success rates as determined by clinical and radiographic evaluation were 75% and 36.7%, respectively; however, the overall success rate of 3Mix non-instrumentation endodontic treatment was 36.7% with 15.8% of cases demonstrating a pulpal response of internal resorption.
Non-instrumentation endodontic treatment using 3Mix-MP showed good clinical success but had a low success rate based on radiographic evaluation at 2-year follow-up. Hence, 3Mix antibiotic treatment cannot replace a conventional root canal treatment agent as a long-term therapy.
评估三种混合抗生素在非器械根管治疗术治疗下颌第一恒磨牙术后 24-27 个月的临床和放射学成功率。
58 名 3-8 岁儿童的 80 颗龋坏的下颌第一恒磨牙接受 3Mix 药物的非器械根管治疗，然后用玻璃离子水门汀和复合树脂密封，最后用不锈钢冠永久修复。患者在 2 年的随访期间每 6 个月接受一次临床和放射学评估，内部检查者可靠性为 0.83-1.00（κ 值）。
在 24-27 个月的随访中，60 例的临床和放射学评估成功率分别为 75%和 36.7%；然而，3Mix 非器械根管治疗的总体成功率为 36.7%，其中 15.8%的病例显示牙髓内吸收反应。
使用 3Mix-MP 的非器械根管治疗显示出良好的临床成功率，但在 2 年的随访中，基于放射学评估的成功率较低。因此，3Mix 抗生素治疗不能替代常规根管治疗剂作为长期治疗。
