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尽管接受了抗骨质疏松治疗，但人类免疫缺陷病毒感染患者仍发生非典型股骨颈应力性骨折：一例报告。

Atypical femoral neck stress fracture in a human immunodeficiency virus-infected patient despite anti-osteoporotic treatment: A case report.

作者信息

Terlemez Rana, Sönmez Mehmet Mesut, Hamidi Aziz Ahmad, Yılmaz Figen

机构信息

Department of Physical Medicine and Rehabilitation, Şişli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

Department of Orthopedics and Traumatology, Şişli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

出版信息

Turk J Phys Med Rehabil. 2020 Aug 18;66(3):364-367. doi: 10.5606/tftrd.2020.4286. eCollection 2020 Sep.

DOI:10.5606/tftrd.2020.4286
PMID:33089094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7557631/
Abstract

Both human immunodeficiency virus (HIV) infection and antiretroviral therapy are related to an increased risk of fracture. As a result of the developments in HIV treatment in recent years, life expectancy in HIV-infected patients has increased. Therefore, HIV-related musculoskeletal problems such as osteoporosis and avascular necrosis are more common currently. There are complex mechanisms in HIV-related osteoporosis. The loss of bone mineral density is particularly distinctive in the first months of the therapy. In this report, we present a 54-year-old woman admitted to our clinic with right thigh pain for three months and diagnosed with a femoral neck stress fracture.

摘要

人类免疫缺陷病毒（HIV）感染和抗逆转录病毒疗法都与骨折风险增加有关。近年来，由于HIV治疗取得进展，HIV感染患者的预期寿命有所延长。因此，诸如骨质疏松症和缺血性坏死等与HIV相关的肌肉骨骼问题目前更为常见。HIV相关骨质疏松症存在复杂的机制。骨矿物质密度的丧失在治疗的最初几个月尤为明显。在本报告中，我们介绍了一名54岁女性，因右大腿疼痛三个月入院，被诊断为股骨颈应力性骨折。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af24/7557631/db0150c93305/TJPMR-2020-66-3-364-367-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af24/7557631/cc3eb663a111/TJPMR-2020-66-3-364-367-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af24/7557631/db0150c93305/TJPMR-2020-66-3-364-367-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af24/7557631/cc3eb663a111/TJPMR-2020-66-3-364-367-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af24/7557631/db0150c93305/TJPMR-2020-66-3-364-367-F2.jpg

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本文引用的文献

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Efficacy of Pharmacological Therapies for the Prevention of Fractures in Postmenopausal Women: A Network Meta-Analysis.绝经后妇女骨折预防的药物治疗效果：网络荟萃分析。
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HIV and Vertebral Fractures: a Systematic Review and Metanalysis.HIV 与椎体骨折：系统评价和荟萃分析。
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