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阿米卡星单独及联合甲氧苄啶-磺胺甲恶唑治疗放线菌性足菌肿

Amikacin alone and in combination with trimethoprim-sulfamethoxazole in the treatment of actinomycotic mycetoma.

作者信息

Welsh O, Sauceda E, Gonzalez J, Ocampo J

机构信息

Department of Dermatology, University Hospital José E. González, Universidad Autónoma de Nuevo León, México.

出版信息

J Am Acad Dermatol. 1987 Sep;17(3):443-8. doi: 10.1016/s0190-9622(87)70227-8.

DOI:10.1016/s0190-9622(87)70227-8
PMID:3308980
Abstract

We report the excellent therapeutic response obtained with amikacin alone and in combination with trimethoprim-sulfamethoxazole in the treatment of 15 patients with actinomycotic mycetoma who had a poor response to the traditional pharmacologic agents and/or in whom important organs such as lungs, spinal cord, and bone were involved. We evaluated the results by clinical, radiologic, and laboratory tests. No important side effects were detected during or after the therapy.

摘要

我们报告了单独使用阿米卡星以及联合使用甲氧苄啶-磺胺甲恶唑治疗15例放线菌性足菌肿患者所取得的优异治疗效果。这些患者对传统药物治疗反应不佳,和/或重要器官如肺、脊髓和骨骼受累。我们通过临床、影像学和实验室检查评估结果。治疗期间及治疗后均未发现严重副作用。

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