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良性血液疾病中的黏弹性检测:即时检测评估止血能力的临床观点和未来意义。

Viscoelastic testing in benign hematologic disorders: Clinical perspectives and future implications of point-of-care testing to assess hemostatic competence.

机构信息

Indiana University School of Medicine, Notre Dame Campus, South Bend, Indiana.

Saint Joseph Regional Medical Center, Mishawaka, Indiana.

出版信息

Transfusion. 2020 Oct;60 Suppl 6:S101-S121. doi: 10.1111/trf.16088.

Abstract

Viscoelastic tests (VETs) have been used routinely for liver transplantation, cardiac surgery, and trauma, but only recently have found clinical utility in benign hematologic disorders. Therefore, guidelines for diagnosis and treatment of these disorders based on viscoelastic variables have been adapted from the existing transplant, cardiothoracic surgery, and trauma resuscitation literature. As a result, diagnostic and therapeutic strategies for benign hematologic disorders utilizing VETs are not uniform. Accordingly, even though there has been a recent increase in the utilization of VET for the diagnosis and treatment of such disorders, the literature is still in its early stages. Analysis of point-of-care viscoelastic tracings from benign hematologic disorders has the potential to allow prompt recognition of disease and to guide patient-specific intervention. Here we present a review describing the application of VETs to benign hematologic disorders.

摘要

黏弹性测试(VETs)已被常规用于肝移植、心脏手术和创伤,但直到最近才在良性血液疾病中发现临床应用价值。因此,基于黏弹性变量的这些疾病的诊断和治疗指南是从现有的移植、心胸外科和创伤复苏文献中改编而来的。因此,利用 VET 诊断和治疗良性血液疾病的诊断和治疗策略并不统一。因此,尽管最近 VET 在这些疾病的诊断和治疗中的应用有所增加,但相关文献仍处于早期阶段。分析良性血液疾病即时黏弹性描记图有可能快速识别疾病,并指导针对患者的干预措施。在这里,我们将介绍一项描述 VET 应用于良性血液疾病的综述。

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