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韩国大动脉炎患者的生存和死因:一项回顾性基于人群的研究。

Survival and causes of death for Takayasu's arteritis in Korea: A retrospective population-based study.

机构信息

Division of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

出版信息

Int J Rheum Dis. 2021 Jan;24(1):69-73. doi: 10.1111/1756-185X.14005. Epub 2020 Oct 22.

Abstract

OBJECTIVE

Few studies have evaluated survival of Takayasu's arteritis (TAK; M31.4) in Korea. The purpose of this study was to assess the survival rate (SR) and causes of death for TAK.

METHODS

Newly diagnosed TAK data (N = 2731) were collected from the National Health Insurance Service in Korea from 2006 through 2017. The Kaplan-Meier method was used. Korean death data was used from 2006 through 2018.

RESULTS

The mean age was 48.1 (±16.9) years. The proportion of female patients was 74.4%. The most common cause of death in TAK was diseases of the circulatory system. The 1-, 3-, 5-, and 10-year SRs were 97.5%, 94.7%, 91.7%, and 84.7%, respectively. The 1-, 3-, 5-, and 10-year SRs by gender were 97.8%, 95.6%, 92.9%, and 86.3%, respectively, among females and 96.8%, 92.2%, 88.4%s and 79.7%, respectively, among males (P < .001).

CONCLUSIONS

The overall 10-year SR was about 85%. The 10-year SR in males was lower than that in females. The most common cause of death in TAK was diseases of the circulatory system.

摘要

目的

鲜有研究评估韩国大动脉炎(TAK;M31.4)的生存率。本研究旨在评估 TAK 的生存率(SR)和死亡原因。

方法

本研究从韩国国家健康保险服务处收集了 2006 年至 2017 年间新诊断的 TAK 数据(N=2731)。采用 Kaplan-Meier 法。韩国死亡数据来源于 2006 年至 2018 年。

结果

患者的平均年龄为 48.1(±16.9)岁。女性患者的比例为 74.4%。TAK 最常见的死亡原因为循环系统疾病。TAK 的 1、3、5 和 10 年 SR 分别为 97.5%、94.7%、91.7%和 84.7%。女性患者的 1、3、5 和 10 年 SR 分别为 97.8%、95.6%、92.9%和 86.3%,男性患者分别为 96.8%、92.2%、88.4%和 79.7%(P<0.001)。

结论

总体 10 年 SR 约为 85%。男性的 10 年 SR 低于女性。TAK 最常见的死亡原因为循环系统疾病。

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