伴随性韧带损伤在桡骨远端骨折后创伤后骨关节炎发展中的作用：系统评价方案。

The role of concomitant ligament injury in the development of post-traumatic osteoarthritis after distal radius fractures: a protocol for a systematic review.

机构信息

Department of Orthopaedic Surgery, Reinier de Graaf Hospital, Delft, The Netherlands

Department of Orthopaedic Surgery, Reinier de Graaf Hospital, Delft, The Netherlands.

出版信息

BMJ Open. 2020 Oct 22;10(10):e039591. doi: 10.1136/bmjopen-2020-039591.

DOI:10.1136/bmjopen-2020-039591

PMID:33093034

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7583071/

Abstract

INTRODUCTION

Treatment of distal radius fractures (DRFs) aims to restore anatomic position of the fracture fragments and congruity of the articular surface to optimise functional outcomes and prevent osteoarthritis in the long term. While ligament injury of the wrist is often associated with DRFs and sole ligament injuries of the wrist lead to osteoarthritis, it is plausible that concomitant ligament injury in DRFs may aggravate degenerative changes of the wrist. The relationship between concomitant ligament injury and post-traumatic osteoarthritis in patients with DRFs is unclear. This study aims to identify the types of associated ligament injury in patients with a DRF and to elucidate the association of ligament injury on the development of post-traumatic osteoarthritis.

METHODS AND ANALYSIS

This protocol is written in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocol (PRISMA-P) guidelines. An electronic search in MEDLINE, Embase, Web of Science, Cochrane Central Register of Trials and Google Scholar has been created and performed by a Health Sciences librarian with expertise in systematic review searching. Original research articles in English literature, which report on concomitant ligament injury of the wrist in relation to post-traumatic osteoarthritis, patient-reported outcome measures or clinician-reported outcome measures in patients (aged ≥18 years) with DRFs will be included. Two reviewers will independently screen and appraise articles and perform data extraction. In case of any disagreements, a third reviewer will be consulted. A systematic qualitative synthesis will be performed using text and tables.

ETHICS AND DISSEMINATION

No ethical approval is required, since this is a protocol for a systematic review. The systematic review will be submitted for publication in a peer-reviewed scientific journal and for presentation at relevant conferences.

PROSPERO REGISTRATION NUMBER

CRD42020165007.

摘要

简介

治疗桡骨远端骨折（DRF）的目的是恢复骨折碎片的解剖位置和关节面的一致性，以优化功能结果并预防长期的骨关节炎。虽然腕部韧带损伤通常与 DRF 相关，且单一的腕部韧带损伤会导致骨关节炎，但 DRF 中同时存在的韧带损伤可能会加重腕部的退行性变化。DRF 患者同时存在的韧带损伤与创伤后骨关节炎之间的关系尚不清楚。本研究旨在确定 DRF 患者伴发的韧带损伤类型，并阐明韧带损伤与创伤后骨关节炎发展之间的关系。

方法和分析

本方案按照系统评价和荟萃分析报告的首选项目（PRISMA-P）指南编写。一名具有系统评价检索专业知识的健康科学图书馆员创建并执行了 MEDLINE、Embase、Web of Science、Cochrane 中央对照试验注册库和 Google Scholar 的电子搜索。纳入的文献为英语文献中的原始研究文章，这些文章报告了与创伤后骨关节炎相关的腕部同时存在的韧带损伤，以及 DRF 患者（年龄≥18 岁）的患者报告结局测量或临床医生报告结局测量。两名审查员将独立筛选和评估文章并进行数据提取。如果存在任何分歧，将咨询第三名审查员。将使用文字和表格进行系统定性综合分析。