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洋葱伯克霍尔德菌K56-2(一种机会致病菌)的全基因组序列

Complete Genome Sequence of Burkholderia cenocepacia K56-2, an Opportunistic Pathogen.

作者信息

García-Romero Inmaculada, Valvano Miguel A

机构信息

Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom.

Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, United Kingdom

出版信息

Microbiol Resour Announc. 2020 Oct 22;9(43):e01015-20. doi: 10.1128/MRA.01015-20.

DOI:10.1128/MRA.01015-20
PMID:33093048
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7585848/
Abstract

K56-2, an opportunistic bacterium for people with cystic fibrosis (CF), belongs to the complex (Bcc) and is consistently used as a model pathogen. We describe here the closed genome sequence for this strain, which will help advance research in biology and omics studies.

摘要

K56-2是囊性纤维化(CF)患者的一种机会致病菌,属于伯克霍尔德菌复合体(Bcc),并一直被用作模式病原体。我们在此描述该菌株的封闭基因组序列,这将有助于推进伯克霍尔德菌生物学和组学研究。

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本文引用的文献

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ET12 transmission in adults with cystic fibrosis.成人囊性纤维化患者中的 ET12 传播。
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2
Performance of neural network basecalling tools for Oxford Nanopore sequencing.基于神经网络的牛津纳米孔测序碱基调用工具的性能。
Genome Biol. 2019 Jun 24;20(1):129. doi: 10.1186/s13059-019-1727-y.
3
Non-Coding RNA Analysis Using the Rfam Database.使用Rfam数据库进行非编码RNA分析。
Curr Protoc Bioinformatics. 2018 Jun;62(1):e51. doi: 10.1002/cpbi.51. Epub 2018 Jun 5.
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Unicycler: Resolving bacterial genome assemblies from short and long sequencing reads.单轮循环器:从短读长和长读长测序数据中解析细菌基因组组装结果
PLoS Comput Biol. 2017 Jun 8;13(6):e1005595. doi: 10.1371/journal.pcbi.1005595. eCollection 2017 Jun.
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Studying RNA Homology and Conservation with Infernal: From Single Sequences to RNA Families.使用Infernal研究RNA同源性和保守性:从单序列到RNA家族
Curr Protoc Bioinformatics. 2016 Jun 20;54:12.13.1-12.13.25. doi: 10.1002/cpbi.4.
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Intracellular survival of Burkholderia cepacia complex in phagocytic cells.洋葱伯克霍尔德菌复合体在吞噬细胞内的存活
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Exaggerated inflammatory responses mediated by Burkholderia cenocepacia in human macrophages derived from Cystic fibrosis patients.伯克霍尔德菌中存在过度的炎症反应,该反应由囊性纤维化患者来源的人巨噬细胞介导。
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