芳基锂与 -芳基吩噻嗪鎓离子的芳基化反应用于联苯合成。
Arylation of aryllithiums with -arylphenothiazinium ions for biaryl synthesis.
机构信息
Department of Chemistry, Faculty of Science, Gakushuin University, 1-5-1 Mejiro, Toshima-ku, Tokyo 171-8588, Japan.
Department of Chemistry, Faculty of Science, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan.
出版信息
Chem Commun (Camb). 2020 Nov 12;56(90):13995-13998. doi: 10.1039/d0cc05830k.
Aryllithiums are one of the most common and important aryl nucleophiles; nevertheless, methods for arylation of aryllithums to produce biaryls have been limited. Herein, we report arylation of aryllithiums with S-arylphenothiazinium ions through selective ligand coupling of intermediary sulfuranes. Various unsymmetrical biaryls could be obtained without transition-metal catalysis.
芳基锂是最常见和最重要的芳基亲核试剂之一；然而，芳基锂的芳基化方法生成联芳烃的方法一直受到限制。在此，我们通过中间体硫𬭩叶立德的选择性配体偶联报告了芳基锂与 S-芳基吩噻嗪鎓离子的芳基化反应。无需过渡金属催化即可获得各种不对称联芳烃。
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