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路邓葡萄球菌皮肤感染:16 例报告。

Staphylococcus lugdunensis Skin Infection: Report of 16 Cases.

机构信息

Unidad de Dermatología, Hospital San Jorge, Huesca, España.

Servicio de Microbiología, Hospital Universitario Miguel Servet, Zaragoza, España.

出版信息

Actas Dermosifiliogr (Engl Ed). 2021 Mar;112(3):261-265. doi: 10.1016/j.ad.2019.05.017. Epub 2020 Oct 20.

Abstract

INTRODUCTION AND OBJECTIVE

Staphylococcus lugdunensis belongs to the group of coagulase-negative staphylococci. The aim of this report was to review the clinical and microbiologic features of cases of S. lugdunensis skin infections.

MATERIAL AND METHODS

Observational study of all cases of skin infections in which S. lugdunensis was isolated by the microbiology department of Hospital General San Jorge in Huesca, Spain, between 2009 and 2016.

RESULTS

We studied the cases of 16 patients. The most frequent site of infection was the inguinal-perineal region (n=6, 37.5%), and pustules were the most common presentation (n=5, 31.3%). Response to treatment was good in 87.6% of the patients (n=14). However, infection recurred in 3 patients, 2 of whom were on anti-TNF therapy.

CONCLUSIONS

S. lugdunensis should be considered a possible cause of infection when it is isolated in both skin and subcutaneous tissues, especially in patients on biologic therapies.

摘要

介绍与目的

路邓葡萄球菌属于凝固酶阴性葡萄球菌群。本报告旨在回顾路邓葡萄球菌皮肤感染的临床和微生物学特征。

材料与方法

对西班牙韦斯卡圣豪尔赫综合医院微生物科 2009 至 2016 年间分离出路邓葡萄球菌的所有皮肤感染病例进行观察性研究。

结果

我们研究了 16 例患者的病例。感染最常见的部位是腹股沟-会阴区(n=6,37.5%),脓疱是最常见的表现(n=5,31.3%)。87.6%的患者(n=14)治疗反应良好。然而,有 3 例患者出现感染复发,其中 2 例正在接受抗 TNF 治疗。

结论

当路邓葡萄球菌在皮肤和皮下组织中同时分离出来时,尤其是在接受生物治疗的患者中,应考虑其为感染的可能原因。

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