Department of Clinical and Experimental Epilepsy, Institute of Neurology, Queen Square, UCL, WC1N 3BG, United Kingdom.
Seizure. 2020 Dec;83:70-75. doi: 10.1016/j.seizure.2020.10.010. Epub 2020 Oct 17.
Magnetoencephalography (MEG) possesses a number of features, including excellent spatiotemporal resolution, that lend itself to the functional imaging of epileptic activity. However its current use is restricted to specific scenarios, namely in the diagnosis refractory focal epilepsies where electroencephalography (EEG) has been inconclusive. This review highlights the recent progress of MEG within epilepsy, including advances in the technique itself such as simultaneous EEG/MEG and intracranial EEG/MEG recording and room temperature MEG recording using optically pumped magnetometers, as well as improved post processing of the data during interictal and ictal activity for accurate source localisation of the epileptogenic focus. These advances should broaden the scope of MEG as an important part of epilepsy diagnostics in the future.
脑磁图（MEG）具有许多特点，包括出色的时空分辨率，非常适合癫痫活动的功能成像。然而，它的当前用途仅限于特定情况，即在脑电图（EEG）结果不确定的情况下，用于诊断难治性局灶性癫痫。本综述强调了 MEG 在癫痫中的最新进展，包括该技术本身的进步，例如同时进行 EEG/MEG 和颅内 EEG/MEG 记录，以及使用光泵磁力计进行室温 MEG 记录，以及在发作间期和发作期对数据进行改进的后处理，以准确定位致痫灶。这些进展应该扩大 MEG 的范围，使其成为未来癫痫诊断的重要组成部分。
