Laparascopy Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Clin Nutr. 2021 Apr;40(4):1755-1766. doi: 10.1016/j.clnu.2020.10.001. Epub 2020 Oct 15.
We performed a meta-analysis to provide quantitative estimates of fat mass (FM) and fat-free mass (FFM) changes in patients following bariatric surgery over 1 year. A systematic search of PubMed, SCOPUS and Web of Science databases was conducted; the pooled weighted mean difference (WMD) and 95% confidence intervals (CI) were calculated using a random-effects model. Thirty-four studies including Roux en-Y gastric bypass (RYGB), sleeve gastrectomy (SG) biliopancreatic diversion (BPD) and gastric banding (GB) were analyzed. RYGB decreased in body FM (-28.99 kg [31.21, -26.77]) or FM% (-12.73% [-15.14, -10.32]) or FFM (-9.97 kg [-10.93, -9.03]), which were greater than SG and GB. Moreover, the FFM% in RYGB group (11.72% [7.33, 16.11]) was more than SG (5.7% [4.44, 6.95]) and GB (8.1% [6.15, 10.05]) groups. Bariatric surgeries, especially RYGB, might be effective for a decrease in FM and maintenance of FFM in patients with morbid obesity in over 1 year.
我们进行了一项荟萃分析，以提供 1 年内接受减重手术后患者体脂肪量（FM）和去脂体重（FFM）变化的定量估计。系统地检索了 PubMed、SCOPUS 和 Web of Science 数据库；使用随机效应模型计算了汇总加权均数差（WMD）和 95%置信区间（CI）。共分析了 34 项研究，包括 Roux-en-Y 胃旁路术（RYGB）、袖状胃切除术（SG）、胆胰分流术（BPD）和胃束带术（GB）。RYGB 可降低体脂肪量（-28.99 公斤 [31.21，-26.77]）或体脂肪百分比（-12.73% [-15.14，-10.32]）或去脂体重（-9.97 公斤 [-10.93，-9.03]），这均大于 SG 和 GB。此外，RYGB 组的去脂体重百分比（11.72% [7.33，16.11]）高于 SG 组（5.7% [4.44，6.95]）和 GB 组（8.1% [6.15，10.05]）。总之，减重手术，尤其是 RYGB，可能对肥胖患者在 1 年以上降低 FM 和维持 FFM 有效。
