Piñól Aguadé J, Palou J, Lecha M, Castel T
Med Cutan Ibero Lat Am. 1977;5(1):1-11.
Four cases with clinical characteristics closely related to Lupus Erythematosus Disseminatum are reported by the authors. The evolution, progress and the biochemical, immunological and photobiological data were different from those usually found in L.E.D. The histopathological picture was also dissimilar, the most characteristic finding being a sharply limited epidermal necrolysis with focal distribution. In view of the peculiarities of the clinico-pathological syndrome presented by these patients, the authors raise the questions does it represent a special modality of L.E.D. or a new lupus-like disease?
作者报告了4例临床特征与播散性红斑狼疮密切相关的病例。其病情演变、进展以及生化、免疫和光生物学数据与播散性红斑狼疮通常所见的不同。组织病理学表现也不相似，最具特征性的发现是局限性分布的、界限清楚的表皮坏死。鉴于这些患者所呈现的临床病理综合征的特殊性，作者提出疑问：它是播散性红斑狼疮的一种特殊类型，还是一种新的狼疮样疾病？
