Division of Vascular and Endovascular Surgery, Boston Medical Center, Boston University School of Medicine, Boston, Mass.
School of Social Work, Boston College, Chestnut Hill, Mass.
J Vasc Surg. 2021 May;73(5):1759-1768.e1. doi: 10.1016/j.jvs.2020.08.156. Epub 2020 Oct 21.
Active smoking among patients undergoing interventions for intermittent claudication (IC) is associated with poor outcomes. Notwithstanding, current levels of active smoking in these patients are high. State-level tobacco control policies have been shown to reduce smoking in the general US population. We evaluated whether state cigarette taxes and 100% smoke-free workplace legislation are associated with active smoking among patients undergoing interventions for IC.
We queried the Vascular Quality Initiative database for peripheral endovascular interventions, infrainguinal bypasses, and suprainguinal bypasses for IC. Active smoking at the time of intervention was defined as smoking within one month of intervention. We implemented difference-in-differences analysis to isolate changes in active smoking owing to cigarette taxes (adjusted for inflation) and implementation of smoke-free workplace legislation. The difference-in-differences models estimated the causal effects of tobacco policies by adjusting for concurrent temporal trends in active smoking unrelated to cigarette taxes or smoke-free workplace legislation. The models controlled for age, sex, race/ethnicity, insurance type, diabetes, chronic obstructive pulmonary disease, state, and year. We tested interactions of taxes with age and insurance.
Data were available for 59,847 patients undergoing interventions for IC in 25 states from 2011 to 2019. Across the study period, active smoking at the time of intervention decreased from 48% to 40%. Every $1.00 cigarette tax increase was associated with a 6-percentage point decrease in active smoking (95% confidence interval, -10 to -1 percentage points; P = .02), representing an 11% decrease relative to the baseline proportion of patients actively smoking. The effect of cigarettes taxes was greater in older patients and those on Medicare. Among patients aged 60 to 69 and 70 to 79 years, every $1.00 tax increase resulted in 14% and 21% reductions in active smoking relative to baseline subgroup prevalences of 53% and 29%, respectively (P < .05 for both); however, younger age groups were not affected by tax increases. Among insurance groups, only patients on Medicare exhibited a significant change in active smoking with every $1.00 tax increase (an 18% decrease relative to a 33% baseline prevalence; P = .01). The number of states implementing smoke-free workplace legislation increased from 9 to 14 by 2019; however, this policy was not significantly associated with active smoking prevalence. At follow-up (median, 12.9 months), $1.00 tax increases were still associated with decreased smoking prevalence (a 25% decrease relative to a 33% baseline prevalence; P < .001).
Cigarette tax increases seem to be an effective strategy to decrease active smoking among patients undergoing interventions for IC. Older patients and Medicare recipients are the most responsive to tax increases.
间歇性跛行(IC)患者中主动吸烟与不良结局有关。尽管如此,这些患者中主动吸烟的比例仍然很高。州级烟草控制政策已被证明可减少美国普通人群的吸烟量。我们评估了州香烟税和 100%无烟工作场所立法是否与 IC 患者接受干预时的主动吸烟有关。
我们查询了血管质量倡议数据库,以获取外周血管腔内介入、下肢旁路术和上肢旁路术治疗 IC 的信息。干预时的主动吸烟定义为在干预前一个月内吸烟。我们实施了差异-差异分析,以确定由于香烟税(经通胀调整)和实施无烟工作场所立法而导致的主动吸烟变化。差异-差异模型通过调整与香烟税或无烟工作场所立法无关的同期主动吸烟的时间趋势,估计了烟草政策的因果效应。该模型控制了年龄、性别、种族/族裔、保险类型、糖尿病、慢性阻塞性肺疾病、州和年份。我们测试了税收与年龄和保险的交互作用。
2011 年至 2019 年,25 个州有 59847 名患者接受 IC 干预,数据可用。在整个研究期间,干预时主动吸烟的比例从 48%降至 40%。每增加 1 美元的香烟税,主动吸烟的比例就会降低 6 个百分点(95%置信区间,-10 至-1 个百分点;P =.02),与基线时主动吸烟的患者比例相比,降低了 11%。在年龄较大和医疗保险患者中,香烟税的效果更大。在 60 至 69 岁和 70 至 79 岁的患者中,每增加 1 美元的税收,与基线亚组患病率(分别为 53%和 29%)相比,主动吸烟的比例分别降低了 14%和 21%(两者均 P<.05);然而,年轻组不受税收增加的影响。在保险组中,只有医疗保险患者的主动吸烟率发生了显著变化,每增加 1 美元的税收,主动吸烟率就会降低 18%(与 33%的基线患病率相比)(P =.01)。到 2019 年,实施无烟工作场所立法的州数量从 9 个增加到 14 个;然而,这一政策与主动吸烟的流行率并没有显著相关。在随访(中位数 12.9 个月)时,增加 1 美元的税收仍然与吸烟率下降有关(与 33%的基线患病率相比,下降 25%;P<.001)。
香烟税的增加似乎是降低 IC 患者主动吸烟的有效策略。年龄较大的患者和医疗保险的受惠者对税收增加的反应最敏感。