Dedov I I, Lukich V L, Bol'shakova T D, Gitel' E P, Dreval' A V
Probl Endokrinol (Mosk). 1987 Jul-Aug;33(4):10-5.
The paper is concerned with the results of a study of the C-peptide concentration in blood serum of 45 patients with type I diabetes mellitus prior to and during therapy with hyperbaric oxygenation (HBO). Each patient was given 10-12 HBO sessions. A HBO therapeutic course was shown to stimulate residual insulin secretion in type I diabetes mellitus with a period of disease not more than 3 years, a daily dose of insulin not more than 60 units, in the absence of excess body mass over 10%, and retinopathy over stage I. Prognostic criteria make it possible to take into account clinical factors in the course of diabetes mellitus preventing the normalization or stimulation of residual basal insulin secretion which can be used for the determination of indications for HBO therapy aimed at the stimulation of insulin secretion.
本文关注对45例1型糖尿病患者在高压氧治疗(HBO)前及治疗期间血清C肽浓度的研究结果。每位患者接受10 - 12次HBO治疗。结果表明,对于病程不超过3年、每日胰岛素剂量不超过60单位、体重超重不超过10%且无I期以上视网膜病变的1型糖尿病患者,HBO治疗疗程可刺激残余胰岛素分泌。预后标准有助于在糖尿病病程中考虑临床因素,这些因素可防止残余基础胰岛素分泌正常化或受到刺激,而这可用于确定旨在刺激胰岛素分泌的HBO治疗指征。