Duke University Medical Center, Durham, North Carolina.
Northwest Dermatology and Research Center, Portland, Oregon.
J Am Acad Dermatol. 2018 Sep;79(3):470-478.e3. doi: 10.1016/j.jaad.2017.10.048. Epub 2017 Nov 8.
Although alopecia areata is a common disorder, it has no US Food and Drug Administration-approved treatment and evidence-based therapeutic data are lacking.
To develop guidelines for the diagnosis, evaluation, assessment, response criteria, and end points for alopecia areata.
Literature review and expert opinion of a group of dermatologists specializing in hair disorders.
Standardized methods of assessing and tracking hair loss and growth, including new scoring techniques, response criteria, and end points in alopecia areata are presented.
The additional time to perform the assessments is the primary limitation to use of the methodology in clinical practice.
Use of these measures will facilitate collection of standardized outcome data on therapeutic agents used in alopecia areata both in clinical practice and in clinical trials.
尽管斑秃是一种常见疾病，但它没有获得美国食品和药物管理局批准的治疗方法，并且缺乏基于证据的治疗数据。
制定斑秃的诊断、评估、评价标准、反应标准和终点的指南。
对一组专门研究毛发疾病的皮肤科医生进行文献回顾和专家意见。
提出了评估和跟踪脱发和生长的标准化方法，包括新的评分技术、斑秃的反应标准和终点。
进行评估的额外时间是在临床实践中使用该方法的主要限制。
使用这些措施将有助于在临床实践和临床试验中收集关于斑秃治疗药物的标准化结果数据。
