Nwagha Theresa, Omotowo Babatunde Ishola
Department of Haematology and Immunology UNTH/Departmant of Haematoogy, AEFUTHA, College of Medicine, Enugu Campus, Enugu State, Nigeria.
Department of Community Medicine, College of Medicine, Enugu Campus, Enugu State, Nigeria.
Niger Med J. 2020 May-Jun;61(3):114-119. doi: 10.4103/nmj.NMJ_122_19. Epub 2020 Jul 4.
With improved understanding of disease mechanism in sickle cell disorder, many persons living with sickle cell disease (SCD) are surviving unto adulthood. There is a growing concern that SCD may impair the psychosocial health-related quality of life (HRQoL), with a resultant lack of psychosocial stability and integration. The objective of this study was to assess the determinants of psychosocial quality of life (QoL) among adults with SCD.
This was a cross-sectional study of adults with SCD. A multidimensional self-administered instrument, prevalidated for use in adults with chronic disease, was used. It consisted of 31 items that assessed physical function, physical and emotional role function, bodily pain, vitality, social function, mental health, and general health within 2 weeks prior to the time of survey. Questionnaires were administered to adults with sickle cell anemia who presented for their routine visit to the Sickle Cell Clinic at the Hematology Clinic in University of Nigeria Teaching Hospital, Ituku-Ozalla Enugu, or during sickle cell support group meetings. Psychosocial HRQoL was the primary outcome measured. Sociodemographic features such as marital status, gender, educational qualification, and SCD were the primary independent variables of interest.
A total of I16 adults with SCD were participated in the study. After adjusting for marital status, gender, and educational qualification of adults with SCD, gender and marital status did not significantly affect psychosocial HRQoL ( = 0.619 and = 0.146), respectively, while educational status significantly affected their HRQoL ( = 0.013).
Adults with SCD have impaired psychosocial HRQoL. There is a need to upscale patient-focused interventions to improve self-esteem and overall QoL.
随着对镰状细胞病发病机制的深入了解，许多镰状细胞病（SCD）患者存活至成年。人们越来越担心SCD可能会损害与心理社会健康相关的生活质量（HRQoL），从而导致心理社会稳定性和融合性的缺乏。本研究的目的是评估成年SCD患者心理社会生活质量（QoL）的决定因素。
这是一项对成年SCD患者的横断面研究。使用了一种经过预验证可用于慢性病成年人的多维自填式工具。它由31个项目组成，评估调查前2周内的身体功能、身体和情感角色功能、身体疼痛、活力、社会功能、心理健康和总体健康状况。对到尼日利亚大学教学医院伊图库-奥扎拉埃努古血液科镰状细胞诊所进行常规就诊的镰状细胞贫血成年患者或在镰状细胞支持小组会议期间发放问卷。心理社会HRQoL是主要测量结果。婚姻状况、性别、教育程度和SCD等社会人口学特征是主要关注的自变量。
共有116名成年SCD患者参与了该研究。在对成年SCD患者的婚姻状况、性别和教育程度进行调整后，性别和婚姻状况分别对心理社会HRQoL没有显著影响（P = 0.619和P = 0.146），而教育程度对其HRQoL有显著影响（P = 0.013）。
成年SCD患者的心理社会HRQoL受损。需要加强以患者为中心的干预措施，以提高自尊和总体QoL。
