Zimmerman M, Coryell W
University of Iowa College of Medicine, Department of Psychiatry, Iowa City 52242.
Psychoneuroendocrinology. 1987;12(4):245-51. doi: 10.1016/0306-4530(87)90048-5.
We have summarized the results of 53 studies which examined the dexamethasone suppression test in normal controls. Only 3.6% of 687 0800 hr postdexamethasone cortisol levels were above 5 micrograms/dl. Corresponding figures for 1600 hr and 2300 hr cortisol levels were 7.4% (85/1144) and 6.3% (28/434), respectively. Neither the type of assay (competitive protein binding or radioimmunoassay) nor mean/median age of the subjects was associated with non-suppression rates.
我们总结了53项针对正常对照者进行地塞米松抑制试验的研究结果。在687名受试者中，地塞米松给药后8点的皮质醇水平仅有3.6%高于5微克/分升。16点和23点皮质醇水平的相应数字分别为7.4%（85/1144）和6.3%（28/434）。检测方法（竞争性蛋白结合法或放射免疫法）以及受试者的平均/中位年龄均与未抑制率无关。
