Ritchie J C, Carroll B J, Olton P R, Shively V, Feinberg M
Arch Gen Psychiatry. 1985 May;42(5):493-7. doi: 10.1001/archpsyc.1985.01790280075007.
Quality control serum samples and postdexamethasone plasma pools were used to compare 16 commercial cortisol radioimmunoassay kits with the competitive protein-binding assay for plasma glucocorticoids that we used to standardize the dexamethasone suppression test (DST). Thirteen radioimmunoassays gave higher criterion values for the DST than those established using the competitive protein-binding assay. The range of radioimmunoassay criterion values was 4.34 to 8.70 mu mg/dL. Possible explanations are given for these findings, and their importance to the clinical utility of the DST are emphasized. Each laboratory should validate its own criterion cortisol value for depression based on local data, including appropriate control groups.
使用质量控制血清样本和地塞米松后血浆池，将16种市售皮质醇放射免疫分析试剂盒与我们用于标准化地塞米松抑制试验（DST）的血浆糖皮质激素竞争性蛋白结合分析法进行比较。13种放射免疫分析给出的DST标准值高于使用竞争性蛋白结合分析法确定的值。放射免疫分析标准值范围为4.34至8.70微克/分升。对这些发现给出了可能的解释，并强调了它们对DST临床应用的重要性。每个实验室应根据当地数据，包括适当的对照组，验证其自身用于抑郁症的皮质醇标准值。
