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基于氨基酸的L-苏氨酸溴化钠的物理化学性质及抗菌性能研究

Studies on physicochemical and antibacterial deeds of amino acid based L-Threoninum sodium bromide.

作者信息

Ashvin Santhia S V, Aneeba B, Vinu S, Sheela Christy R, Al-Mohaimeed Amal M, Al Farraj Dunia A

机构信息

Department of Physics and Research Centre, Nesamony Memorial Christian College, Marthandam, Affiliated to Manonmaniam Sundaranar University, Abishekapatti Tirunelveli, Tamil Nadu, India.

Department of Physics, Government Arts and Science College, Nagercoil, India.

出版信息

Saudi J Biol Sci. 2020 Nov;27(11):2987-2992. doi: 10.1016/j.sjbs.2020.09.020. Epub 2020 Sep 17.

Abstract

Highly translucent nonlinear single crystals of L-Threoninum Sodium Bromide (LTSB) has been grown because of their rising need for everyday life and the XRD studies (PXRD and SXRD) solemnly affirmed the crystallinity and non-centrosymmetric space group of LTSB materials. The bonding nature and diverse functional groups in LTSB were demonstrated by FTIR analysis when they absorb infrared radiation. The optical behavior of LTSB crystals was explored through UV-Vis spectroscopy, which shows optical parameters depend on photon energy with band gap E = 5.7 eV which was suitable for optoelectronic devices. The electrical properties of LTSB crystals were measured by using dielectric measurement. The solid state parameters of LTSB crystal were calculated. An antibacterial activity developed by LTSB crystals against different pathogenic bacteria were examined using the Agar disk diffusion process. The antibacterial inhibitory activity of LTSB crystal revealed that it can be used to treat a variety of bacterial infections.

摘要

由于日常生活中对L-苏氨酸溴化钠(LTSB)的需求不断增加,已经生长出了高度透明的非线性单晶,并且X射线衍射研究(粉末X射线衍射和单晶X射线衍射)郑重地证实了LTSB材料的结晶性和非中心对称空间群。当LTSB吸收红外辐射时,通过傅里叶变换红外光谱分析证明了其键合性质和多样的官能团。通过紫外-可见光谱探索了LTSB晶体的光学行为,结果表明光学参数取决于光子能量,其带隙E = 5.7电子伏特,适用于光电器件。通过介电测量来测量LTSB晶体的电学性质。计算了LTSB晶体的固态参数。使用琼脂扩散法检测了LTSB晶体对不同病原菌的抗菌活性。LTSB晶体的抗菌抑制活性表明它可用于治疗多种细菌感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95c7/7569142/39a6c5bb072e/gr1.jpg

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