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非梗阻性无精子症伴双侧睾丸萎缩的不育男性成功进行睾丸精子提取:一例报告

Successful testicular sperm extraction in infertile male with non-obstructive azoospermia presented with bilateral atrophic testis: A case report.

作者信息

Adriansjah Ricky, Kusumajaya Christopher, Wijayanti Zola

机构信息

Urology Department, Hasan Sadikin Academic Medical Center, Faculty of Medicine Universitas Padjajaran, Bandung, Indonesia.

出版信息

Urol Case Rep. 2020 Jun 16;33:101300. doi: 10.1016/j.eucr.2020.101300. eCollection 2020 Nov.

DOI:10.1016/j.eucr.2020.101300
PMID:33102003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7573833/
Abstract

Approximately 50% of men with NOA have minimal sperm production within their dysfunctional testes. Studies shown poor correlations between testicular size and sperm retrieval rates. A 34 years old man with NOA and bilateral testicular atrophic had a successful sperm extraction using mTESE from his 2.1 cc right testicle. Lower testicular volumes significantly decrease sperm retrieval rate in mTESE. However, we described a successful mTESE in atrophic testis. Therefore, small testicular volume does not affect the successful rate of mTESE and should not be a contraindication.

摘要

大约50%的非梗阻性无精子症男性在其功能失调的睾丸内有极少的精子生成。研究表明睾丸大小与取精成功率之间的相关性较差。一名34岁患有非梗阻性无精子症和双侧睾丸萎缩的男性,通过显微睾丸精子提取术(mTESE)从其2.1立方厘米的右侧睾丸中成功提取出了精子。在mTESE中,较小的睾丸体积会显著降低取精成功率。然而,我们描述了在萎缩睾丸中成功进行mTESE的案例。因此,睾丸体积小并不影响mTESE的成功率,不应成为禁忌证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66d3/7573833/97985234aef0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66d3/7573833/a2dd5c297168/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66d3/7573833/5b724d446ab0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66d3/7573833/97985234aef0/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66d3/7573833/a2dd5c297168/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66d3/7573833/5b724d446ab0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66d3/7573833/97985234aef0/gr3.jpg

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本文引用的文献

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Andrologia. 2019 Dec;51(11):e13441. doi: 10.1111/and.13441. Epub 2019 Oct 4.
2
Sperm retrieval by microdissection testicular sperm extraction and intracytoplasmic sperm injection outcomes in nonobstructive azoospermic patients with Klinefelter syndrome.克氏综合征非梗阻性无精子症患者经显微外科睾丸取精术取精及卵胞浆内单精子注射的结局
Andrologia. 2018 Feb 20. doi: 10.1111/and.12983.
3
Severe testicular atrophy does not affect the success of microdissection testicular sperm extraction.
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J Urol. 2014 Jan;191(1):175-8. doi: 10.1016/j.juro.2013.07.065. Epub 2013 Aug 1.
4
The epidemiology and etiology of azoospermia.少精子症的流行病学和病因学。
Clinics (Sao Paulo). 2013;68 Suppl 1(Suppl 1):15-26. doi: 10.6061/clinics/2013(sup01)03.