Nasution Rosnani, Muhabbah Nurul, Helwati Hira, Bahi Muhammad, Marianne Marianne, Amna Ulil
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.
J Adv Pharm Technol Res. 2020 Jul-Sep;11(3):148-156. doi: 10.4103/japtr.JAPTR_6_20. Epub 2020 Jul 14.
The purpose of this research is to find a lupeol acetate from fruit peel. Ethyl acetate extract of fruit peel was obtained by maceration process. After the process of fractionation, it results 3 subfractions (A, B, and C). The subfraction B was rechromatographed and yielded B2 pure isolate. Based on data from proton nuclear magnetic resonance, Fourier transform-infrared, and mass spectrometry (MS from gas chromatography-MS), the B2 isolate was suspected as lupeol acetate compound (in this study, the presence of lupeol acetate in the fruit peel has been reported for the first time).
本研究的目的是从果皮中找到一种乙酸羽扇豆醇酯。通过浸渍法获得果皮的乙酸乙酯提取物。经过分馏过程,得到3个亚组分(A、B和C)。对亚组分B进行再色谱分离,得到B2纯分离物。根据质子核磁共振、傅里叶变换红外光谱和质谱(气相色谱 - 质谱联用的质谱)数据,怀疑B2分离物为乙酸羽扇豆醇酯化合物(在本研究中,首次报道了果皮中存在乙酸羽扇豆醇酯)。