磁性纳米材料在骨组织修复中的最新进展

Fan Daoyang, Wang Qi, Zhu Tengjiao, Wang Hufei, Liu Bingchuan, Wang Yifan, Liu Zhongjun, Liu Xunyong, Fan Dongwei, Wang Xing

Department of Orthopedic, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Department of Pediatrics, Peking University Third Hospital, Beijing, China.

Front Chem. 2020 Sep 25;8:745. doi: 10.3389/fchem.2020.00745. eCollection 2020.

The magnetic field has been proven to enhance bone tissue repair by affecting cell metabolic behavior. Magnetic nanoparticles are used as biomaterials due to their unique magnetic properties and good biocompatibility. Through endocytosis, entering the cell makes it easier to affect the physiological function of the cell. Once the magnetic particles are exposed to an external magnetic field, they will be rapidly magnetized. The magnetic particles and the magnetic field work together to enhance the effectiveness of their bone tissue repair treatment. This article reviews the common synthesis methods, the mechanism, and application of magnetic nanomaterials in the field of bone tissue repair.

磁场已被证明可通过影响细胞代谢行为来促进骨组织修复。磁性纳米颗粒因其独特的磁性和良好的生物相容性而被用作生物材料。通过内吞作用进入细胞，使其更容易影响细胞的生理功能。一旦磁性颗粒暴露于外部磁场，它们将迅速被磁化。磁性颗粒与磁场共同作用，增强其骨组织修复治疗的效果。本文综述了磁性纳米材料在骨组织修复领域的常见合成方法、作用机制及应用。