维生素 C 作为缓解普通感冒症状的补充疗法：10 项随机对照试验的荟萃分析。
Vitamin C as a Supplementary Therapy in Relieving Symptoms of the Common Cold: A Meta-Analysis of 10 Randomized Controlled Trials.
机构信息
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
Department of Occupational and Environmental Health, School of Health Sciences, Wuhan University, Wuhan 430071, China.
出版信息
Biomed Res Int. 2020 Oct 9;2020:8573742. doi: 10.1155/2020/8573742. eCollection 2020.
AIM
To investigate whether vitamin C performs well as a supplemental treatment for common cold.
METHOD
After systematically searching through the National Library of Medicine (PubMed), Cochrane Library, Elsevier, China National Knowledge Infrastructure (CNKI), VIP databases, and Wanfang databases, 10 randomized controlled trials were selected for our meta-analysis with RevMan 5.3 software. Published in China, all 10 studies evaluated the effect of combined vitamin C and antiviral therapy for the treatment of common cold.
RESULTS
The total efficacy (RR = 1.27, 95% CI (1.08, 1.48), = 0.003), the time for symptom amelioration (MD = -15.84, 95% CI (-17.02, -14.66), < 0.00001), and the time for healing (, 95% CI (-14.98, -4.22), = 0.0005) were better with vitamin C supplementation than with antiviral therapy alone.
CONCLUSIONS
Vitamin C could be used as a supplementary therapy along with antiviral regimens to relieve patients from the symptoms of common cold.
目的
探讨维生素 C 作为普通感冒辅助治疗的效果。
方法
通过系统检索美国国立医学图书馆（PubMed）、考科兰协作网（Cochrane Library）、爱思唯尔（Elsevier）、中国知网（CNKI）、维普及万方数据库，纳入使用维生素 C 联合抗病毒药物治疗普通感冒的随机对照试验，采用 RevMan 5.3 软件进行荟萃分析。10 项研究均在中国发表，评价了维生素 C 联合抗病毒治疗普通感冒的疗效。
结果
维生素 C 组总有效率[RR=1.27，95%CI（1.08，1.48）， =0.003]、症状缓解时间[MD=-15.84，95%CI（-17.02，-14.66）， ＜0.00001]、痊愈时间[MD=-4.22，95%CI（-14.98，-4.22）， =0.0005]均优于抗病毒治疗组。
结论
维生素 C 可作为一种辅助治疗方法与抗病毒药物联合应用，以缓解普通感冒患者的症状。
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