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肝门部胆管癌孤立性盆腔复发导致的直肠狭窄

Rectal stenosis due to solitary pelvic recurrence of hilar cholangiocarcinoma.

作者信息

Shioi Ikuma, Yamaoka Yusuke, Shiomi Akio, Kagawa Hiroyasu, Hino Hitoshi, Manabe Shoichi, Aizawa Daisuke

机构信息

Division of Colon and Rectal Surgery Shizuoka Cancer Center Sunto-gun Japan.

Division of Pathology Shizuoka Cancer Center Sunto-gun Japan.

出版信息

JGH Open. 2020 May 16;4(5):1014-1016. doi: 10.1002/jgh3.12357. eCollection 2020 Oct.

Abstract

An 85-year-old woman was admitted to a hospital with abdominal pain. Five years prior to admission, she had a history of hilar cholangiocarcinoma of pStage IIIC. Contrast-enhanced computed tomography showed a mass between the rectum and uterus as well as bowel obstruction due to the lesion. Colonoscopy showed severe stenosis at the lower rectum and elevation of the submucosal layer with linear erosion. Rectal cancer was suspected, and pelvic recurrence of hilar cholangiocarcinoma or endometrial carcinoma infiltrating the rectum was considered as differential diagnosis. She underwent robot-assisted low anterior resection combined with partial resection of the uterus. The immunohistopathological findings of the resected specimen favored a diagnosis of metastasis of cholangiocarcinoma, rather than primary rectal cancer or endometrial carcinoma. There were no signs of recurrence after 10 months of follow-up. Hilar cholangiocarcinoma is a disease with poor prognosis. Recurrence is frequently experienced even after curative resection. Patients with recurrence are rarely candidates for re-resection. However, better prognosis is reported for those with complete resection.

摘要

一名85岁女性因腹痛入院。入院前5年,她有IIIC期肝门部胆管癌病史。增强计算机断层扫描显示直肠与子宫之间有一肿块,且该病变导致肠梗阻。结肠镜检查显示直肠下段严重狭窄,黏膜下层隆起并伴有线性糜烂。怀疑为直肠癌,鉴别诊断考虑肝门部胆管癌盆腔复发或子宫内膜癌浸润直肠。她接受了机器人辅助低位前切除术联合子宫部分切除术。切除标本的免疫组织病理学检查结果支持胆管癌转移的诊断,而非原发性直肠癌或子宫内膜癌。随访10个月后无复发迹象。肝门部胆管癌是一种预后较差的疾病。即使进行了根治性切除,也经常会复发。复发患者很少适合再次手术。然而,据报道,完全切除的患者预后较好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a345/7578318/7062003868af/JGH3-4-1014-g001.jpg

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