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[A randomized controlled study on the efficacy of inhaled nitric oxide in treatment of neonates with meconium aspiration syndrome].吸入一氧化氮治疗新生儿胎粪吸入综合征疗效的随机对照研究
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Inhaled NO at a crossroads in cardiac surgery: current need to improve mechanistic understanding, clinical trial design and scientific evidence.心脏手术中吸入一氧化氮正处于十字路口：当前需要提高对其作用机制的理解、改进临床试验设计并加强科学证据。
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本文引用的文献

1
Poractant Alfa Versus Beractant for Neonatal Respiratory Distress Syndrome: A Retrospective Cost Analysis.肺泡表面活性物质阿尔法与贝拉克坦治疗新生儿呼吸窘迫综合征的回顾性成本分析
J Pediatr Pharmacol Ther. 2018 Sep-Oct;23(5):367-371. doi: 10.5863/1551-6776-23.5.367.
2
Inhaled nitric oxide therapy for pulmonary disorders of the term and preterm infant.吸入一氧化氮治疗足月儿和早产儿的肺部疾病。
Semin Perinatol. 2016 Oct;40(6):356-369. doi: 10.1053/j.semperi.2016.05.007.
3
Inhaled nitric oxide in term/late preterm neonates with hypoxic respiratory failure: estimating the financial impact of earlier use.足月/晚期早产儿缺氧性呼吸衰竭吸入一氧化氮治疗：评估早期使用的经济影响
J Med Econ. 2015;18(8):612-8. doi: 10.3111/13696998.2015.1038270. Epub 2015 May 7.
4
Cost of inhaled nitric oxide therapy in neonates.
Lancet. 2002 May 18;359(9319):1781-2. doi: 10.1016/S0140-6736(02)08632-4.

新生儿一氧化氮治疗的成本。

Cost of nitric oxide therapy in neonates.

作者信息

Hoyle Emily, Spierson Hannah, Cordon David, Brady Joanne, Subhedar Nimish V

机构信息

Neonatal Unit, Liverpool Womens Hospital NHS Foundation Trust, Liverpool, UK.

出版信息

BMJ Paediatr Open. 2020 Oct 13;4(1):e000776. doi: 10.1136/bmjpo-2020-000776. eCollection 2020.

DOI:10.1136/bmjpo-2020-000776
PMID:33102801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7554454/
Abstract

A retrospective observational cohort study was performed to review the cost of inhaled nitric oxide (iNO) therapy in a UK neonatal intensive care setting over a 4-year period. 188 neonates with a median (IQR) gestational age and birth weight of 27 (24-37) weeks and 980 (695-2812) g, respectively, were treated with iNO. The median (IQR) duration of iNO therapy was 60 (22-129) hours. The mean cost of iNO therapy was approximately £820 per baby treated equivalent to £8.50 per hour of therapy. Alternative pricing models suggested a calculated cost of iNO therapy of between approximately £950 and £1350 per baby.

摘要

开展了一项回顾性观察队列研究，以评估英国新生儿重症监护环境下4年期间吸入一氧化氮（iNO）治疗的成本。188例新生儿接受了iNO治疗，其胎龄中位数（四分位间距）和出生体重分别为27（24 - 37）周和980（695 - 2812）克。iNO治疗的中位数（四分位间距）持续时间为60（22 - 129）小时。iNO治疗的平均成本约为每位接受治疗的婴儿820英镑，相当于每小时治疗费用为8.50英镑。其他定价模型显示，iNO治疗的计算成本约为每位婴儿950至1350英镑。