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一名接种卡介苗(BCG)的患者发生肺结核合并新型冠状病毒肺炎(COVID-19)感染:病例报告

Coinfection of Tuberculosis Pneumonia and COVID-19 in a Patient Vaccinated with Bacille Calmette-Guérin (BCG): Case Report.

作者信息

Luciani Michelangelo, Bentivegna Enrico, Spuntarelli Valerio, Amoriello Lamberti Piera, Guerritore Ludovica, Chiappino Dario, Nalli Gabriele, Proietta Maria, Del Porto Flavia, Martelletti Paolo, Sesti Giorgio

机构信息

Faculty of Medicine and Psychology, Department of Clinical and Molecular Medicine, Internal Medicine Unit, Sant'Andrea University Hospital, Sapienza University, Rome, Italy.

Faculty of Medicine and Psychology, Emergency Medicine CoViD-19 Unit, Sant'Andrea University Hospital, Sapienza University, Rome, Italy.

出版信息

SN Compr Clin Med. 2020;2(11):2419-2422. doi: 10.1007/s42399-020-00601-9. Epub 2020 Oct 17.

Abstract

COVID-19 is a respiratory tract infection caused by the new coronavirus SARS-COV2 that can be complicated by acute distress respiratory syndrome and multiorgan failure. In light of the high rate of mortality associated with COVID-19, pharmacological and non-pharmacological strategies to prevent the infection are currently being tested. Among non-pharmacological preventive measures, vaccines represent one of the main resources for public health. It has been suggested that Bacille Calmette-Guérin (BCG) vaccine may protect individuals against infection from COVID-19 virus, and two clinical trials addressing this question are underway. Here, we report the case of a 32-year-old woman, vaccinated with BCG when she was 1 year old, who was diagnosed with apical tuberculous pneumonia of the right lung along with COVID 19 pneumonia.

摘要

新型冠状病毒肺炎(COVID-19)是由新型冠状病毒SARS-CoV-2引起的呼吸道感染,可并发急性呼吸窘迫综合征和多器官功能衰竭。鉴于与新型冠状病毒肺炎相关的高死亡率,目前正在测试预防感染的药理学和非药理学策略。在非药理学预防措施中,疫苗是公共卫生的主要资源之一。有人提出,卡介苗(BCG)疫苗可能会保护个体免受新型冠状病毒肺炎病毒的感染,针对这一问题的两项临床试验正在进行中。在此,我们报告一例32岁女性病例,该女性1岁时接种过卡介苗,被诊断为右肺尖结核性肺炎合并新型冠状病毒肺炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bad/7568690/ef6f4a00ee08/42399_2020_601_Fig1_HTML.jpg

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