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获得性癫痫性失语:诊断44年后

Acquired epileptiform aphasia: 44 years after diagnosis.

作者信息

Jokel Regina, Meloff Keith

机构信息

Baycrest Health Sciences, Rotman Research Institute, University of Toronto, Toronto, Ontario, Canada.

Section on Neurology, Ontario Medical Association, Toronto, Ontario, Canada.

出版信息

Epilepsy Behav Rep. 2020 Aug 31;14:100388. doi: 10.1016/j.ebr.2020.100388. eCollection 2020.

Abstract

We report a case of a 48-year-old woman who was diagnosed with Landau-Kleffner syndrome (LKS) at the age of 4 and reassessed by the same neurologist four decades later. While her seizures abated by the time she was 12 years old, she was left with chronic aphasia, despite receiving optimal care. Although she graduated from high school, started her own family, and was gainfully employed, she was vulnerable in situations that required clear communication. This case reflects successful management of an otherwise debilitating condition and reminds us of the vulnerability of adults with LKS and their need for a life-long support.

摘要

我们报告了一例48岁女性病例,该患者4岁时被诊断为Landau-Kleffner综合征(LKS),40年后由同一位神经科医生进行重新评估。尽管她12岁时癫痫发作停止,但尽管接受了最佳治疗,仍留下了慢性失语症。虽然她高中毕业、组建了自己的家庭并拥有一份有收入的工作,但在需要清晰沟通的情况下她仍很脆弱。该病例反映了对一种原本会使人衰弱的疾病的成功管理,并提醒我们LKS成年患者的脆弱性以及他们对终身支持的需求。

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Acquired epileptiform aphasia: 44 years after diagnosis.获得性癫痫性失语:诊断44年后
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本文引用的文献

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Epidemiological study of Landau-Kleffner syndrome (LKS) in Japan.日本 Landau-Kleffner 综合征(LKS)的流行病学研究。
Brain Dev. 2014 Apr;36(4):284-6. doi: 10.1016/j.braindev.2013.04.012. Epub 2013 May 21.
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The Landau-Kleffner Syndrome.兰道-克莱夫纳综合征
Epilepsy Curr. 2001 Nov;1(2):39-45. doi: 10.1111/j.1469-5812.2005.00134.x-i1.

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