Department of Chemistry, Institute of Exact Sciences, Federal University of Amazonas, Manaus, Brazil.
Chemistry Institute, Brazilian Doping Control Laboratory (LBCD - LADETEC/IQ - UFRJ), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Nat Prod Res. 2022 Feb;36(4):984-988. doi: 10.1080/14786419.2020.1837823. Epub 2020 Oct 26.
The metabolic fingerprint of a non-volatile fraction of (Rich.) Mez (Lauraceae) leaves was determined by UHPLC-HRMS analysis. Twenty-four compounds were suggestively identified by GNPS-FBMN. The results revealed a large production of flavonoids, mainly flavones and flavanones, a chemical class poorly described in the genus. Within the identified compounds, four are being described for the first time in this genus. The major metabolite detected was astilbin, with a concentration corresponding to 23.2 ± 1.58% of the extracts. The expressive content of astilbin also highlights it as a chemical marker for the species. As a species that is classified as a complex, qualitative and semi-quantitative features obtained through the flavonoid fingerprint can be further used for a more precise circumscription and species-specific characterization.
通过 UHPLC-HRMS 分析，确定了（Rich.）Mez（Lauraceae）叶子的非挥发性部分的代谢指纹图谱。通过 GNPS-FBMN 提示鉴定出 24 种化合物。结果表明，该植物大量产生黄酮类化合物，主要为黄酮类和黄烷酮类，这是该属中描述较少的一类化学物质。在所鉴定的化合物中，有 4 种是首次在该属中描述的。检测到的主要代谢产物是紫云英苷，其浓度相当于提取物的 23.2±1.58%。紫云英苷的高含量也使其成为该物种的化学标志物。作为一种被归类为复杂种的物种，通过黄酮指纹图谱获得的定性和半定量特征可进一步用于更精确的界定和种特异性特征描述。
