Soufi Alexandra, Gouton Marielle, Metton Olivier, Mitchell Julia, Bernard Yvette F, Bozio Andre, Ninet Jean, Di Filippo Sylvie
Cardiology Department, Jean Minjoz University Medical Center, Besançon, France.
Congenital Cardiology Department, Cardiovascular Hospital Louis Pradel, Hospices Civils de Lyon, Lyon, France.
Cardiol Young. 2021 Jan;31(1):97-104. doi: 10.1017/S1047951120003431. Epub 2020 Oct 26.
Progress in the management of complex congenital heart disease (CHD) led to an improvement in survival rates of adults with a Fontan-like circulation. The objective of this study was to assess the subjective health status and quality of life of this population.
Patients aged more than 18 years at the time of the study, who underwent a Fontan-like procedure. Subjective health status was assessed by the SF-36 questionnaire and a linear analog scale was used to score patients' self-perception of their quality of life; cardiac and demographic parameters were collected.
Among 65 eligible patients, 60 (23 females; mean ± SD age: 25.7 ± 7.2 years) answered the SF-36 questionnaire and 46 of these were interviewed to evaluate their perceived quality of life. Among them, 20 (33.3%) were working full-time and 21 (35%) experienced arrhythmias. The physical SF-36 scores were lower in patients than in the general population (p ≤ 0.05). The New York Hear Association (NYHA) class and occupation were correlated with SF-36 scores of physical activity (respectively, p = 0.0001 and p = 0.025). SF-36 scores of psychological status were associated with the number of drugs and occupation (respectively, p = 0.0001 and p = 0.02). The mean ± SD quality of life score measured using a linear analog scale was 7.02 ± 1.6 and was linked to education and occupation (p ≤ 0.05) but not with cardiac parameters.
Adult Fontan patients perceive an impaired physical health but report a good overall quality of life. Education and occupation impacts significantly on Fontan patients' quality of life.
复杂先天性心脏病（CHD）管理方面的进展使具有类Fontan循环的成年患者生存率得到提高。本研究的目的是评估该人群的主观健康状况和生活质量。
研究时年龄超过18岁且接受了类Fontan手术的患者。通过SF-36问卷评估主观健康状况，并使用线性模拟量表对患者的生活质量自我认知进行评分；收集心脏和人口统计学参数。
在65例符合条件的患者中，60例（23例女性；平均±标准差年龄：25.7±7.2岁）回答了SF-36问卷，其中46例接受访谈以评估其感知的生活质量。其中，20例（33.3%）全职工作，21例（35%）经历过心律失常。患者的身体SF-36评分低于一般人群（p≤0.05）。纽约心脏协会（NYHA）分级和职业与身体活动的SF-36评分相关（分别为p = 0.0001和p = 0.025）。心理状态的SF-36评分与药物数量和职业相关（分别为p = 0.0001和p = 0.02）。使用线性模拟量表测得的生活质量平均±标准差评分为7.02±1.6，与教育和职业相关（p≤0.05），但与心脏参数无关。
成年Fontan患者感觉身体健康受损，但报告总体生活质量良好。教育和职业对Fontan患者的生活质量有显著影响。
