Mackowiak P A
Medical Service, Veterans Administration Medical Center, Dallas, TX 75216.
Am J Med Sci. 1987 Oct;294(4):275-86. doi: 10.1097/00000441-198710000-00011.
Although drug fever is a clinical entity that has received considerable attention in textbooks and review articles, only recently have such writings been subjected to critical analysis. In the present review, mechanisms responsible for drug fever are examined. In addition, published characterizations of the syndrome are compared with the results of a recently published systematic analysis of 148 cases of drug fever. This comparison identified a number of important areas in which descriptions of the clinical entity in textbooks and review articles are at odds with the clinical profile exhibited by actual cases of drug fever.
尽管药物热是一种在教科书和综述文章中受到广泛关注的临床病症，但直到最近这些著述才受到批判性分析。在本综述中，对引起药物热的机制进行了研究。此外，将已发表的该综合征的特征与最近发表的对148例药物热病例的系统分析结果进行了比较。这种比较确定了一些重要领域，在这些领域中，教科书和综述文章中对该临床病症的描述与药物热实际病例所呈现的临床特征不一致。
