丁丙诺啡对精神分裂症的抗精神病作用。
Antipsychotic effect of buprenorphine in schizophrenia.
作者信息
Schmauss C, Yassouridis A, Emrich H M
机构信息
Max Planck Institute for Psychiatry, Munich.
出版信息
Am J Psychiatry. 1987 Oct;144(10):1340-2. doi: 10.1176/ajp.144.10.1340.
PMID:3310672
Abstract
The antipsychotic potency of the partial opiate agonist buprenorphine was evaluated in 10 neuroleptic-free schizophrenic patients suffering from frequent hallucinations, delusions, and severe formal thought disorders. Buprenorphine had a pronounced antipsychotic effect, which lasted about 4 hours, in patients with schizophreniform disorders (N = 4) and paranoid schizophrenia (N = 3).
摘要
在10名未服用抗精神病药物、频繁出现幻觉、妄想及严重形式思维障碍的精神分裂症患者中，评估了部分阿片受体激动剂丁丙诺啡的抗精神病效力。丁丙诺啡对精神分裂症样障碍患者（n = 4）和偏执型精神分裂症患者（n = 3）有显著的抗精神病作用，持续约4小时。
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