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老年脑室出血患者行脑室外引流后易发生感染。

Older patients with intraventricular hemorrhage are prone to infection after external ventricular drainage.

机构信息

Department of Neurosurgery, University of Health Sciences Gülhane Training and Research Hospital, Ankara-Turkey.

出版信息

Ulus Travma Acil Cerrahi Derg. 2020 Nov;26(6):870-874. doi: 10.14744/tjtes.2020.06159.

DOI:10.14744/tjtes.2020.06159
PMID:33107953
Abstract

BACKGROUND

External ventricular drainage (EVD) is a life-saving and emergent procedure in neurosurgery. However, infection is the main problem in patients with EVD. The present study aims to analyze the infection rate of patients with EVD and to investigate the factors that contribute to infection and mortality rates.

METHODS

The data of patients who underwent emergent EVD procedure between 2018 and 2019 were retrospectively analyzed in this study. The demographic features of the patients were recorded. The correlation between age, gender, indication and duration of EVD, and the infection and mortality rate were investigated.

RESULTS

In this study, 47 patients underwent emergent EVD in two years. Thirty (63.83%) patients were male, and 17 were female with a mean age of 28.02 years. The mean duration of drainage was 6.2 days. Fifty-eight cerebrospinal fluid (CSF) samples were analyzed during the drainage period and CSF culture was positive in 14 (24.14%) samples. The most common microorganism was Staphylococcus epidermidis. The infection rate was high in older and male patients with duration longer than six days. Nine (19.15%) patients died during the treatment period and six of them had IVH.

CONCLUSION

The duration of EVD should be shorter in patients older than 65 years with the diagnosis of intraventricular hemorrhage, which is mostly related to dea.

摘要

背景

脑外科中,脑室外引流术(EVD)是一种救命的紧急手术。然而,感染是 EVD 患者的主要问题。本研究旨在分析 EVD 患者的感染率,并探讨导致感染和死亡率的因素。

方法

本研究回顾性分析了 2018 年至 2019 年期间接受紧急 EVD 手术的患者数据。记录患者的人口统计学特征。研究了年龄、性别、EVD 适应证和持续时间与感染和死亡率之间的相关性。

结果

在本研究中,两年内有 47 名患者接受了紧急 EVD。30 名(63.83%)患者为男性,17 名患者为女性,平均年龄为 28.02 岁。引流时间平均为 6.2 天。在引流期间分析了 58 份脑脊液(CSF)样本,其中 14 份(24.14%)样本 CSF 培养阳性。最常见的微生物是表皮葡萄球菌。感染率在年龄较大和男性患者中较高,且引流时间超过六天。9 名(19.15%)患者在治疗期间死亡,其中 6 名患有 IVH。

结论

对于诊断为脑室内出血的 65 岁以上患者,EVD 的持续时间应更短,这主要与死亡率有关。

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Older patients with intraventricular hemorrhage are prone to infection after external ventricular drainage.老年脑室出血患者行脑室外引流后易发生感染。
Ulus Travma Acil Cerrahi Derg. 2020 Nov;26(6):870-874. doi: 10.14744/tjtes.2020.06159.
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Combination of Conventional EVD and Ommaya Drainage for Intraventricular Hemorrhage (IVH).传统 EVD 与 Ommaya 引流联合治疗脑室出血(IVH)。
Clin Interv Aging. 2024 Jan 3;19:1-10. doi: 10.2147/CIA.S436522. eCollection 2024.
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Construction and validation of infection risk model for patients with external ventricular drainage: a multicenter retrospective study.构建并验证脑室外引流患者感染风险模型:一项多中心回顾性研究。
Acta Neurochir (Wien). 2023 Nov;165(11):3255-3266. doi: 10.1007/s00701-023-05771-8. Epub 2023 Sep 11.