Honkonen E, Erkkola R
Department of Obstetrics and Gynecology, University Central Hospital, Turku, Finland.
Ann Chir Gynaecol Suppl. 1987;202:14-6.
The antibacterial activity against Escherichia coli K 12 in 153 samples of amniotic fluid (AF) in 15 to 40 weeks of pregnancy were investigated by a new micromethod. Fifty-six mothers had an uncomplicated pregnancy while various complications (maternal diabetes, cholestasis of pregnancy, pregnancy induced hypertension, blood group isoimmunization and fetal growth retardation) were present in 97 cases. A significant (p less than 0.001) improvement of antibacterial activity was observed with advancing pregnancy. The highest antibacterial activity in AF was observed in cases with intrauterine growth retardation. In other respects the effect of various diseases was negligible.
采用一种新的微量法对153份妊娠15至40周羊水样本针对大肠杆菌K12的抗菌活性进行了研究。56名母亲妊娠过程顺利，而97例存在各种并发症（妊娠糖尿病、妊娠胆汁淤积症、妊娠高血压、血型同种免疫和胎儿生长受限）。随着孕周增加，观察到抗菌活性有显著（p<0.001）改善。羊水抗菌活性最高值出现在胎儿宫内生长受限的病例中。在其他方面，各种疾病的影响可忽略不计。
