Friedrichs Anette, Kramme Evelyn, Weis Sebastian, Pletz Mathias
Antibiotic Stewardship, Campus Kiel, Universitätsklinikum Schleswig-Holstein, Kiel, Deutschland.
Klinik für Infektiologie und Mikrobiologie, Campus Lübeck, Universitätsklinikum Schleswig-Holstein, Lübeck, Deutschland.
Med Klin Intensivmed Notfmed. 2021 Feb;116(1):81-92. doi: 10.1007/s00063-020-00745-5. Epub 2020 Oct 27.
Antibiotic resistance is a part of bacterial evolution and therefore unavoidable. Scarcity of novel treatment options requires prudent use of available antibiotics in order to decelerate the spread of resistance. This is the aim of antibiotic stewardship (ABS) programmes. The implementation of strategies that optimize antibiotic prescription and therapy necessitates the deployment of personnel as well as of structural resources. Necessary requirements for staff and strategies based on their evidence are described in the updated German S3 ABS Guideline. In the future, patients with infectious diseases will benefit from accelerated microbiological diagnostics as early adequate treatment not only reduces antibiotic consumption but also improves patient outcome. In addition, training of infectious disease specialists will substantially contribute to enhanced quality of care of patients with infectious disease.
抗生素耐药性是细菌进化的一部分，因此不可避免。新型治疗选择的稀缺性要求谨慎使用现有抗生素，以减缓耐药性的传播。这就是抗生素管理（ABS）计划的目标。实施优化抗生素处方和治疗的策略需要配备人员以及结构性资源。最新的德国S3 ABS指南描述了基于证据的人员必要要求和策略。未来，传染病患者将受益于加速的微生物诊断，因为早期的充分治疗不仅能减少抗生素的使用，还能改善患者的治疗效果。此外，传染病专家的培训将极大地有助于提高传染病患者的护理质量。
