Brüngger A, Brülisauer M, Mitsuhashi Y, Schneider B V, Bollinger A, Schnyder U W
Dermatological Clinic, University Hospital Zürich, Switzerland.
Arch Dermatol Res. 1987;279 Suppl:S24-9. doi: 10.1007/BF00585916.
A 50-year-old male patient had three episodes of acrally located purpura within 12 years without any other symptoms. The first two episodes which lasted several months coincided with the intake of beta-blockers; the third episode developed after a respiratory infection. A cryofibrinogenemia was found without any evidence of an underlying primary disease, especially not of a neoplasm. The clinical, histological, immunohistological, and electron microscopical findings, as well as the results obtained by intravital fluorescence videomicroscopy are presented.
一名50岁男性患者在12年内出现三次肢端紫癜，无其他症状。前两次发作持续数月，与服用β受体阻滞剂同时发生；第三次发作在呼吸道感染后出现。发现有冷纤维蛋白原血症，但无潜在原发性疾病的证据，尤其是无肿瘤证据。本文介绍了临床、组织学、免疫组织学和电子显微镜检查结果，以及活体荧光视频显微镜检查结果。
