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儿童面部小侵袭性肿块的放射学诊断难题:鉴别诊断需要增加:炎症性肌纤维母细胞瘤。

Radiological diagnostic dilemma in a child with small aggressive facial mass, time to increase the differentials: an inflammatory myofibroblastic tumour.

机构信息

Radiology and Medical Imaging, King Saud University Medical City, Riyadh, Saudi Arabia.

Radiology and Medical Imaging, King Saud University Medical City, Riyadh, Saudi Arabia

出版信息

BMJ Case Rep. 2020 Oct 27;13(10):e235532. doi: 10.1136/bcr-2020-235532.

Abstract

A 5-year-old girl with left facial swelling in the medial maxillary region close to the nasal ala was brought by her parents to our head and neck clinic. They have visited other doctors for similar presentation in the last 6 months, which started as redness and swelling, with occasional epiphora. The redness resolved after medical treatment, with slight regression of swelling, although it did not disappear. CT and MRI showed a locally aggressive, small enhancing soft tissue mass involving the left anteromedial maxillary wall, the nasal bone and the orbital floor. The mass involved the bony course of the nasolacrimal duct, which was the aetiology of the epiphora. The head and neck team performed an incisional biopsy through a sublabial approach. Concurrently, a nasolacrimal duct stent was inserted by an ophthalmologist. Histopathology was consistent with inflammatory myofibroblastic tumour with positive stains for CD68, CD163 and anaplastic lymphoma kinase-1. The tumour was excised and presently the patient is on periodic follow-up with head and neck and ophthalmology clinics.

摘要

一位 5 岁女孩因左面部上颌窦区靠近鼻翼出现肿胀,由父母带到我们的头颈部诊所就诊。在过去的 6 个月里,他们曾因类似的表现看过其他医生,最初的症状是红肿,偶尔伴有溢泪。红肿经药物治疗后消退,肿胀略有消退,但并未完全消失。CT 和 MRI 显示局部侵袭性、小范围强化的软组织肿块累及左上颌窦前内侧壁、鼻骨和眶底。肿块累及鼻泪管的骨段,这是溢泪的病因。头颈部团队通过经唇下入路进行了切开活检。同时,眼科医生插入了鼻泪管支架。组织病理学检查符合炎性肌纤维母细胞瘤,CD68、CD163 和间变性淋巴瘤激酶-1 染色阳性。肿瘤已被切除,目前患者定期到头颈和眼科诊所进行随访。

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