Korlepara Rajani, Guttikonda Venkateswara Rao, Madala Jayakiran, Taneeru Sravya
Department of Oral Pathology and Microbiology, Mamata Dental College, Khammam, Telangana, India.
J Oral Maxillofac Pathol. 2017 Jan-Apr;21(1):136-139. doi: 10.4103/jomfp.JOMFP_122_15.
Inflammatory pseudotumor is a term given to different neoplastic and nonneoplastic entities that have a common histological appearance, which comprises spindle cell proliferation with a prominent chronic inflammatory cell infiltrate. Inflammatory myofibroblastic tumor (IMT) is an uncommon lesion with distinctive clinical, pathological and molecular features and is considered to be pseudotumor for the past two decades due to its appearance. IMT is an intermediate soft tissue tumor which was first observed in lungs. It was named as IMT because it mimics a malignant neoplasm clinically, radiologically and histopathologically. The most common sites are lungs, liver and gastrointestinal tract. IMT in head and neck region is exceptionally rare and the sites reported include gingiva, tongue, hard palate, mandible, buccal mucosa and submandibular salivary gland. Till now, 8 cases of intramandibular IMT were reported. Here, we report an additional case of intramandibular IMT in a 20-year-old male patient.
炎性假瘤是一个用于描述具有共同组织学表现的不同肿瘤性和非肿瘤性实体的术语，其组织学表现为梭形细胞增殖并伴有显著的慢性炎性细胞浸润。炎性肌纤维母细胞瘤（IMT）是一种具有独特临床、病理和分子特征的罕见病变，由于其外观，在过去二十年中一直被视为假瘤。IMT是一种中间型软组织肿瘤，最初在肺部被观察到。它被命名为IMT是因为其在临床、放射学和组织病理学上都类似于恶性肿瘤。最常见的部位是肺、肝和胃肠道。头颈部区域的IMT极为罕见，已报道的部位包括牙龈、舌、硬腭、下颌骨、颊黏膜和下颌下唾液腺。到目前为止，已报道了8例下颌骨内IMT。在此，我们报告1例20岁男性患者的下颌骨内IMT病例。
