亚甲蓝的光致诱变性研究。
A study of the photoinduced mutagenicity of methylene blue.
作者信息
Gutter B, Speck W T, Rosenkranz H S
出版信息
Mutat Res. 1977 Aug;44(2):177-82. doi: 10.1016/0027-5107(77)90075-6.
PMID:331101
Abstract
Illumination of Salmonella typhimurium strains in the presence of methylene blue resulted in the production of mutations of the base-substitution type. This photodynamic effect mediated by the dye was separable from the genetic event seen when bacteria are illuminated in the absence of added photosensitizers.
摘要
在亚甲蓝存在的情况下对鼠伤寒沙门氏菌菌株进行光照，会导致碱基替换类型的突变产生。这种由染料介导的光动力效应与在不添加光敏剂的情况下对细菌进行光照时所观察到的遗传事件是可分离的。
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