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口腔恶性黑色素瘤：一种侵袭性且罕见的疾病实体。

Malignant Melanoma of the Oral Cavity: An Aggressive and Rare Entity.

作者信息

Sharma Preeti, Wadhwan Vijay, Tyagi Sonam, Sharma Rishabh

机构信息

Department of Oral & Maxillofacial Pathology & Oral Microbiology, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh 250005 India.

Kasturba Medical College, Manipal, Karnataka 576104 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4842-4845. doi: 10.1007/s12070-024-04899-y. Epub 2024 Jul 15.

DOI:10.1007/s12070-024-04899-y
PMID:39376289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11456140/
Abstract

It is exceptionally unusual to see oral malignant melanoma, which is highly aggressive with dismal prognosis. A 61-year-old female patient presented with hyperpigmented and hemorrhagic areas in the anterior mandible. Microscopically, positive Immunohistochemistry staining with monoclonal antibody Human Melanoma Black (HMB45) and S100 protein, confirmed the diagnosis as malignant melanoma.

摘要

口腔恶性黑色素瘤极为罕见，其侵袭性很强，预后很差。一名61岁女性患者下颌前部出现色素沉着和出血区域。显微镜下，单克隆抗体人黑色素瘤黑色（HMB45）和S100蛋白免疫组化染色呈阳性，确诊为恶性黑色素瘤。

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本文引用的文献

1
A Case Report of Oral Malignant Melanoma: A Silent Killer.口腔恶性黑色素瘤病例报告：隐匿的杀手
Cureus. 2023 Mar 25;15(3):e36671. doi: 10.7759/cureus.36671. eCollection 2023 Mar.
2
Histopathological evaluation of cutaneous malignant melanoma: A retrospective study.皮肤恶性黑色素瘤的组织病理学评估：一项回顾性研究。
Exp Ther Med. 2022 Jun;23(6):402. doi: 10.3892/etm.2022.11329. Epub 2022 Apr 20.
3
Extensive malignant melanoma of the oral cavity: a rare occurrence.口腔广泛性恶性黑色素瘤：一种罕见病例。
Autops Case Rep. 2021 Aug 20;11:e2021299. doi: 10.4322/acr.2021.299. eCollection 2021.
4
Melanoma of the oral cavity: A silent killer.口腔黑色素瘤：隐匿的杀手。
Ann Med Surg (Lond). 2021 Jan 18;62:182-185. doi: 10.1016/j.amsu.2021.01.026. eCollection 2021 Feb.
5
Primary Malignant Melanoma of Oral Mucosa - Report of Two Cases.口腔黏膜原发性恶性黑色素瘤——两例报告
Contemp Clin Dent. 2020 Apr-Jun;11(2):195-198. doi: 10.4103/ccd.ccd_380_19. Epub 2020 Aug 7.
6
Premalignant and malignant oral mucosal lesions: Clinical and pathological findings.癌前病变和恶性口腔黏膜病变：临床和病理表现。
J Am Acad Dermatol. 2019 Jul;81(1):59-71. doi: 10.1016/j.jaad.2018.09.060. Epub 2018 Nov 14.
7
Oral malignant melanoma: A case report with review of literature.口腔恶性黑色素瘤：一例病例报告并文献复习
Contemp Clin Dent. 2014 Jul;5(3):415-8. doi: 10.4103/0976-237X.137978.
8
Oral malignant melanoma: A silent killer?口腔恶性黑色素瘤：沉默的杀手？
J Indian Soc Periodontol. 2011 Oct;15(4):425-8. doi: 10.4103/0972-124X.92587.
9
Primary oral mucosal melanoma: a series of 35 new cases from South America.原发性口腔黏膜黑色素瘤：来自南美洲的35例新病例系列
Am J Dermatopathol. 2009 Jun;31(4):323-30. doi: 10.1097/DAD.0b013e3181a0d37c.
10
Malignant melanoma of the oral cavity.口腔恶性黑色素瘤
Indian J Dent Res. 2006 Apr-Jun;17(2):94-6. doi: 10.4103/0970-9290.29882.