口腔恶性黑色素瘤：一种侵袭性且罕见的疾病实体。
Malignant Melanoma of the Oral Cavity: An Aggressive and Rare Entity.
作者信息
Sharma Preeti, Wadhwan Vijay, Tyagi Sonam, Sharma Rishabh
机构信息
Department of Oral & Maxillofacial Pathology & Oral Microbiology, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh 250005 India.
Kasturba Medical College, Manipal, Karnataka 576104 India.
出版信息
Indian J Otolaryngol Head Neck Surg. 2024 Oct;76(5):4842-4845. doi: 10.1007/s12070-024-04899-y. Epub 2024 Jul 15.
Abstract
It is exceptionally unusual to see oral malignant melanoma, which is highly aggressive with dismal prognosis. A 61-year-old female patient presented with hyperpigmented and hemorrhagic areas in the anterior mandible. Microscopically, positive Immunohistochemistry staining with monoclonal antibody Human Melanoma Black (HMB45) and S100 protein, confirmed the diagnosis as malignant melanoma.
摘要
口腔恶性黑色素瘤极为罕见，其侵袭性很强，预后很差。一名61岁女性患者下颌前部出现色素沉着和出血区域。显微镜下，单克隆抗体人黑色素瘤黑色（HMB45）和S100蛋白免疫组化染色呈阳性，确诊为恶性黑色素瘤。
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