Iqbal Suhail, Malik Mehak, Bano Gulshan
Department of Obstetrics & Gynecology, Government Medical College, Baramulla, J&K, India.
J Family Med Prim Care. 2020 Aug 25;9(8):4323-4328. doi: 10.4103/jfmpc.jfmpc_900_20. eCollection 2020 Aug.
The association of gestational diabetes mellitus and serum Vitamin D levels in different trimesters of pregnancy has been studied recently. We conducted this study in an prospective observational cohort of well-characterized healthy pregnant women to examine the relationship between 1 trimester Vitamin D levels and Gestational Diabetes Mellitus (GDM) status during pregnancy.
All pregnant women attending the out-patient department of Gynecology & Obstetrics, aged less than 35 years, and who were in their first trimester were included in the study. Socio-demographic, anthropometric details, clinical details, food frequency questionnaire and physical activity data was collected using validated pretested questionnaire.
The comparison between those with GDM and those with normal glucose levels has been illustrated. Women in the GDM are older than those in the non-GDM group. The women in GDM group were taller, heavier and their BMI was greater than those in the non-GDM group. There were no significant differences in dietary intake at baseline between mothers with GDM and those with normal glucose levels. Further, it was found that Vitamin D concentration of <30 nmol/L was found among higher among those with GDM and the relationship was statistically significant.
There is an association between maternal Vitamin D deficiency and increased risk for GDM in early pregnancy among Kashmiri women.
近期已有关于妊娠不同阶段妊娠期糖尿病与血清维生素D水平之间关联的研究。我们在一个特征明确的健康孕妇前瞻性观察队列中开展了本研究，以探讨孕早期维生素D水平与妊娠期糖尿病（GDM）状态之间的关系。
纳入所有年龄小于35岁、处于孕早期且到妇产科门诊就诊的孕妇。使用经过验证和预测试的问卷收集社会人口统计学、人体测量学细节、临床细节、食物频率问卷和身体活动数据。
已对患有GDM者与血糖水平正常者进行了比较。患有GDM的女性比非GDM组的女性年龄更大。GDM组的女性更高、更重，且其体重指数大于非GDM组的女性。患有GDM的母亲与血糖水平正常的母亲在基线时的饮食摄入量无显著差异。此外，发现GDM患者中维生素D浓度<30 nmol/L的比例更高，且这种关系具有统计学意义。
克什米尔女性中，孕早期母体维生素D缺乏与GDM风险增加之间存在关联。
