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伴有严重心脏毒性的牛角瓜中毒:一例报告

Calotropis poisoning with severe cardiac toxicity A case report.

作者信息

Iyadurai Ramya, Gunasekaran Karthik, Jose Arun, Pitchaimuthu Kishore

机构信息

Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.

Department of Biochemistry, Christian Medical College, Vellore, Tamil Nadu, India.

出版信息

J Family Med Prim Care. 2020 Aug 25;9(8):4444-4447. doi: 10.4103/jfmpc.jfmpc_783_20. eCollection 2020 Aug.

Abstract

Calotropis is a widely prevalent plant in the Indian Subcontinent. The extract and various parts of the plant are used by traditional healers for treating miscellaneous diseases. All parts of the plants are toxic; there are many case reports of gastrointestinal, cutaneous and ocular toxicity with Calotropis. The plant contains Cardenolide glycosides which have Digoxin like effects and can cause severe cardiotoxicity. We report a patient who developed cardiovascular collapse after oral ingestion and cutaneous application of Calotropis following snake bite by a traditional healer, this case thus highlights the potential cardiotoxicity of Calotropis.

摘要

牛角瓜是印度次大陆一种广泛分布的植物。传统治疗师使用该植物的提取物和各个部位来治疗多种疾病。该植物的所有部位都有毒;有许多关于牛角瓜导致胃肠道、皮肤和眼部毒性的病例报告。这种植物含有具有地高辛样作用的强心苷,可引起严重的心脏毒性。我们报告了一名患者,在被传统治疗师用牛角瓜治疗蛇咬伤后,口服并皮肤涂抹牛角瓜后出现心血管衰竭,该病例因此凸显了牛角瓜潜在的心脏毒性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d066/7586564/0a886eba9d8c/JFMPC-9-4444-g001.jpg

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